Trevor W. Robbins

TL;DR: The neural correlate of trait impulsiveness in the OFC matches an area where brain function has previously been related to inhibitory control and the data show for the first time structural correlates of both cognitive functioning and impulsivity in healthy adolescent subjects.

TL;DR: The authors showed that dopamine depletion from the sulcus principalis of the monkey prefrontal cortex specifically impaired spatial working memory, as measured in the delayed response task, and these deficits were remediated by drugs such as L-dopa and apomorphine, thus opening up a new era of potential therapeutic approaches in treating the cognitive deficits in such neurological and neuropsychiatric disorders such as Parkinson's disease, attention deficit hyperactivity disorder, schizophrenia and phenylketonuria.

TL;DR: A critique of key animal models for selected OC spectrum disorders is provided, beginning with initial work relating to anxiety, but moving on to recent developments in domains of genetic, pharmacological, cognitive, and ethological models.

TL;DR: In this paper, the effects of functional polymorphisms of the dopamine transporter gene (DAT1) and the COMT gene were investigated using a visuospatial and numerical n-back working memory paradigm.

TL;DR: An up‐to‐date conceptualization of genetic variations influencing neurocognitive functions in schizophrenia patients is developed and several genetic variations have emerged as having preliminary effects on neuroc cognitive deficits in schizophrenia.