Trevor W. Robbins

TL;DR: This review will review the current models of behavioral inhibition along with their expression via underlying brain regions, including those involved in the activation of the brain's emergency 'brake' operation, those engaged in more controlled and sustained inhibitory processes and other ancillary executive functions.

TL;DR: The results indicate that the vulnerability to stimulant addiction may depend on an impulsivity endophenotype, and characterize in neurobehavioral and neurochemical terms a rodent model of impulsivity based on premature responding in an attentional task.

TL;DR: Evidence is presented that the nucleus basalis-neocortical cholinergic system contributes greatly to visual attentional function, but not to mnemonic processes per se, and it is suggested that nucleus basali-amygdala cholinerential projections have a role in the retention of affective conditioning while brainstem cholinery projections to the thalamus and midbrain dopamine neurons affect basic arousal processes.

TL;DR: It is anticipated that a greater understanding of the prefrontal cortex will come from using tasks that load specific cognitive and executive processes, in parallel with discovering new ways of manipulating the different sub-regions and neuromodulatory systems of the cortex.

TL;DR: Patients with unilateral or bilateral frontal lobe excisions were compared with age and IQ matched controls on a computerized battery of tests of spatial working memory and planning, revealing an impairment of higher cognitive functioning following frontal lobe damage.