Trevor W. Robbins

TL;DR: The results suggest that the use of specific pharmacological agents targeting α2 and β noradrenergic receptors may improve existing treatments for attentional deficits and impulsivity, whereas DA D3 receptors may modulate error monitoring and perseverative behaviour.

TL;DR: Lesions of the central nucleus of the amygdala did not impair the performance of positively reinforced discriminated approach, nor did they impair the acquisition of a new response with conditioned reinforcement, however, the potentiation of responding with CR following intra-accumbens amphetamine was blocked in lesioned animals.

TL;DR: The findings show that amphetamine-derived stimulants have both short- and long-term consequences for psychomotor functioning, and the demonstration of residual deficits in rats chronically exposed to MDMA raises some concern about the potential harm caused by this drug in human ecstasy users.

TL;DR: In this article, the NIHR Cambridge Biomedical Research Centre with additional support from the Cambridge Home and EU Scholarship Scheme, the James F McDonnell Foundation (21st Century Science Initiative for Understanding Human Cognition), Wellcome Trust (103838); Medical Research Council (MC US A060 0016, and RG62761), the Cambridge Brain Bank, PSP Association and the Evelyn Trust.

TL;DR: Alterations in the "response-setting" process alone and both the response-setting and "response inhibition" process probably arise from striatal pathology in HD, thus accounting for the task-switching deficits and showing how basal ganglia implemented response processes may underpin executive function.