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Tsung-Hsien Chuang

Researcher at National Health Research Institutes

Publications -  58
Citations -  11455

Tsung-Hsien Chuang is an academic researcher from National Health Research Institutes. The author has contributed to research in topics: Receptor & Toll-like receptor. The author has an hindex of 32, co-authored 57 publications receiving 10546 citations. Previous affiliations of Tsung-Hsien Chuang include La Jolla Institute for Allergy and Immunology & Scripps Research Institute.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.

Catherine Werts, +16 more
- 01 Apr 2001 - 
TL;DR: It is shown that for intact L. interrogans, it is LPS, not lipoprotein, that constitutes the predominant signaling component for macrophages through a TLR2 pathway, providing a basis for understanding the innate immune response caused by leptospirosis.
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Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7

Jongdae Lee, +7 more
- 27 May 2003 - 
TL;DR: Evidence is presented that guanosine analogs activate immune cells via TLR7 by a pathway that requires endosomal maturation, and the B cell-stimulating and antiviral activities of the guanosin analogs may be explained by theirTLR7-activating capacity.
Journal Article

Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9

Tsung-Hsien Chuang, +1 more
- 06 Oct 2000 - 
TL;DR: Phylogenetic analysis shows that constitutively active hTLR7-9 belong to a new sub-family of the hTLRs, indirectly supporting the contention that these receptors are involved in cellular responses to stimuli, which activate innate immunity.
Journal ArticleDOI

Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells

Tsung-Hsien Chuang, +1 more
- 19 Mar 2001 - 
TL;DR: HTLR10 mRNA is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil, and Expression analysis of cell lines indicates a predominance in a variety of immune cell types, and is preferentially expressed in tissues and cells involved in immune responses.