T
Tuomas Hätinen
Researcher at University of Helsinki
Publications - 2
Citations - 132
Tuomas Hätinen is an academic researcher from University of Helsinki. The author has contributed to research in topics: Glial cell line-derived neurotrophic factor & Neurturin. The author has an hindex of 2, co-authored 2 publications receiving 127 citations.
Papers
More filters
Journal ArticleDOI
Evolution of the GDNF family ligands and receptors.
TL;DR: The presence of RET- and GFR-like genes in insects suggests that a ProtoGFR and a ProtoRET arose early in the evolution of bilaterian animals, but when the ProtoGFL diverged from existing transforming growth factor (TGFβ)-like proteins remains unclear.
Journal ArticleDOI
Loss of neurturin in frog--comparative genomics study of GDNF family ligand-receptor pairs.
TL;DR: Analysis of exon structures suggests a common origin of GFR-superfamily proteins and early divergence of Gas1 from the common ancestor, and evolutionary trace analysis and protein structure homology modeling points at GDNF as the endogenous ligand of frog GFRalpha2.