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Ufuk Gündüz

Bio: Ufuk Gündüz is an academic researcher from Middle East Technical University. The author has contributed to research in topics: Hydrogen production & Photofermentation. The author has an hindex of 44, co-authored 206 publications receiving 6560 citations. Previous affiliations of Ufuk Gündüz include Military Academy & University of Tennessee Health Science Center.


Papers
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Journal ArticleDOI
TL;DR: A summary of the hydrogen production metabolism of the photosynthetic purple non-sulfur (PNS) bacteria will be presented, showing that under certain conditions, alternative modes of metabolism are also possible and should be considered in experimental design.

460 citations

Journal ArticleDOI
TL;DR: In this paper, the chitosan-coated magnetic nanoparticles (CSMNPs) were in situ synthesized by cross-linking method using tripolyphosphate (TPP).
Abstract: The chitosan-coated magnetic nanoparticles (CS MNPs) were in situ synthesized by cross-linking method. In this method; during the adsorption of cationic chitosan molecules onto the surface of anionic magnetic nanoparticles (MNPs) with electrostatic interactions, tripolyphosphate (TPP) is added for ionic cross-linking of the chitosan molecules with each other. The characterization of synthesized nanoparticles was performed by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS/ESCA), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), dynamic light scattering (DLS), thermal gravimetric analysis (TGA), and vibrating sample magnetometry (VSM) analyses. The XRD and XPS analyses proved that the synthesized iron oxide was magnetite (Fe3O4). The layer of chitosan on the magnetite surface was confirmed by FTIR. TEM results demonstrated a spherical morphology. In the synthesis, at higher NH4OH concentrations, smaller sized nanoparticles were obtained. The average diameters were generally between 2 and 8 nm for CS MNPs in TEM and between 58 and 103 nm in DLS. The average diameters of bare MNPs were found as around 18 nm both in TEM and DLS. TGA results indicated that the chitosan content of CS MNPs were between 15 and 23 % by weight. Bare and CS MNPs were superparamagnetic. These nanoparticles were found non-cytotoxic on cancer cell lines (SiHa, HeLa). The synthesized MNPs have many potential applications in biomedicine including targeted drug delivery, magnetic resonance imaging (MRI), and magnetic hyperthermia.

270 citations

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TL;DR: This study obtained an effective targeted delivery system for Doxorubicin, using chitosan coated MNPs, which have pH responsive release characteristics and can provide new insights in the development of pH responsive targeted drug delivery systems to overcome the side effects of conventional chemotherapy.

246 citations

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TL;DR: The results show that hydrogen production is decreased when the initially inoculated bacteria have a high culture age and the implementation of a light–dark cycle illumination scheme for emulating natural sunlight is implemented.

226 citations

Journal ArticleDOI
TL;DR: A role is suggested for endogenous C18-ceramide synthesis mainly via hLASS1 in imatinib-induced apoptosis in sensitive cells, whereas in resistant cells, alterations of the balance between the levels of ceramide and S1P by overexpression of SK1 result in resistance to imatin ib-mediated apoptosis.

220 citations


Cited by
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Journal ArticleDOI
23 Oct 2008-Nature
TL;DR: By measuring and mathematically modelling changes in the levels of products of metabolism found in biological fluids and tissues, metabonomics offers fresh insight into the effects of diet, drugs and disease.
Abstract: Organisms often respond in complex and unpredictable ways to stimuli that cause disease or injury. By measuring and mathematically modelling changes in the levels of products of metabolism found in biological fluids and tissues, metabonomics offers fresh insight into the effects of diet, drugs and disease.

1,633 citations

Journal ArticleDOI
TL;DR: In this paper, a review article summarizes bio-hydrogen production from some waste materials, including cellulose and starch containing agricultural and food industry wastes and some food industry wastewaters.

1,569 citations

Journal ArticleDOI
TL;DR: In this paper, an overview of these technologies for hydrogen production from biomass is presented. And the future development will also be addressed, as well as future development of the future technologies.

1,065 citations