Ulf Sjögren

TL;DR: The predictability from clinical and radiographic signs of the treatment-outcome in individual cases with preoperative periapical lesions cases was found to be low and factors which were not measured or identified may be critical to the outcome of endodontic treatment.

TL;DR: The microbial flora in canals after failed endodontic therapy differed markedly from the flora in untreated teeth, and infection at the time of root filling and size of the periapical lesion had a negative influence on the prognosis.

TL;DR: This study investigated the role of infection on the prognosis of endodontic therapy by following-up teeth that had had their canals cleaned and obturated during a single appointment, highlighting the importance of completely eliminating bacteria from the root canal system before obturation.

TL;DR: The antibacterial effect of calcium hydroxide as a short-term intracanal dressing was clinically evaluated and showed that the 7-day dressing efficiently eliminated bacteria which survived biomechanical instrumentation of the canal, while the 10-minute application was ineffective.

TL;DR: In the majority of root-filled human teeth with therapy-resistant periapical lesions, microorganisms may persist and may play a significant role in endodontic treatment failures, in certain instances such lesions may also be sustained by foreign body giant cell type of tissue responses at the periapex ofRoot-filled teeth.