U
Ulrich Bogdahn
Researcher at University of Regensburg
Publications - 347
Citations - 36060
Ulrich Bogdahn is an academic researcher from University of Regensburg. The author has contributed to research in topics: Neural stem cell & Neurogenesis. The author has an hindex of 67, co-authored 344 publications receiving 32279 citations. Previous affiliations of Ulrich Bogdahn include Hoffmann-La Roche & Volkswagen Foundation.
Papers
More filters
Journal ArticleDOI
Transforming growth factor-beta-mediated autocrine growth regulation of gliomas as detected with phosphorothioate antisense oligonucleotides.
Piotr Jachimczak,Birgit Hessdörfer,Klaus Fabel-Schulte,Cäcilie Wismeth,Wolfgang Brysch,Karl-Hermann Schlingensiepen,Albrecht Bauer,Armin Blesch,Ulrich Bogdahn +8 more
TL;DR: It is postulate that the endogenously produced TGF‐β2 control glioma‐cell proliferation is regulated in part by an intracellular loop.
Journal ArticleDOI
Stem Cell Quiescence in the Hippocampal Neurogenic Niche Is Associated With Elevated Transforming Growth Factor-β Signaling in an Animal Model of Huntington Disease
Mahesh Kandasamy,Sebastien Couillard-Despres,Kerstin Raber,Michael Stephan,Bernadette Lehner,Beate Winner,Zacharias Kohl,Francisco J. Rivera,Huu Phuc Nguyen,Olaf Riess,Ulrich Bogdahn,Jürgen Winkler,Stephan von Hörsten,Ludwig Aigner +13 more
TL;DR: The results indicate that alterations in neurogenesis in transgenic Huntington disease rats occur in successive phases that are associated with increasing TGF-&bgr; signaling, which seems to be a crucial modulator of neuroGenesis in Huntington disease and may represent a target for future therapy.
Journal ArticleDOI
TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons.
Mahesh Kandasamy,Bernadette Lehner,Sabrina Kraus,Paul Ramm Sander,Paul Ramm Sander,Julia Marschallinger,Francisco J. Rivera,Dietrich Trümbach,Uwe Ueberham,Herbert A. Reitsamer,Olaf Strauss,Ulrich Bogdahn,Sebastien Couillard-Despres,Ludwig Aigner +13 more
TL;DR: The results demonstrate that TGF‐β1 promotes stem cell quiescence on one side, but also neuronal survival on the other side, which presents a molecular target for future interventions in ageing and neurodegenerative diseases.
Journal ArticleDOI
Safety and feasibility of long-term temozolomide treatment in patients with high-grade glioma
Peter Hau,Dorothee Koch,Thomas Hundsberger,E. Marg,B. Bauer,R. Rudolph,Michael Rauch,Andrew Brenner,P. Rieckmann,J. Schuth,Tanja Jauch,Horst J. Koch,Ulrich Bogdahn +12 more
TL;DR: It is suggested that long-term treatment with temozolomide is feasible and well tolerated and a small percentage of patients experienced grade III to IV toxicity.
Journal ArticleDOI
Neuronal precursor-specific activity of a human doublecortin regulatory sequence.
Claudia Karl,Sebastien Couillard-Despres,Peter Prang,Matthias Munding,Werner Kilb,Tanja Brigadski,Sonja Plötz,Wolfgang Mages,Heiko J. Luhmann,Jürgen Winkler,Ulrich Bogdahn,Ludwig Aigner +11 more
TL;DR: The doublecortin (DCX) gene encodes a 40‐kDa microtubule‐associated protein specifically expressed in neuronal precursors of the developing and adult CNS and it is demonstrated by transient transfection experiments that this fragment is sufficient and specific to drive expression of reporter genes in embryonic and adult neurons.