Ulrich Reininghaus

TL;DR: The study of psychotic experiences is helping to elucidate the mechanisms by which environmental and genetic influences shape the transdiagnostic expression of psychosis proneness, that is mostly transitory but may first become persistent over time and eventually give rise to transition to a psychotic disorder.

TL;DR: The aims and current foci of the HiTOP Consortium, a group of 70 investigators working together to study empirical classification of psychopathology, are described, which pertain to continued research on the empirical organization of psychopathological constructs; the connection between personality and psychopathology; the utility of empirically based psychopathology constructs in both research and the clinic.

TL;DR: Overall, although a number of considerations and challenges remain, ESM offers one of the best opportunities for personalized medicine in psychiatry, from both a research and a clinical perspective.

TL;DR: The Hierarchical Taxonomy of Psychopathology (HiTOP) as discussed by the authors is based on empirical patterns of co-occurrence among psychological symptoms, and it has the potential to accelerate and improve research on mental health problems as well as efforts to more effectively assess, prevent, and treat mental illness.

TL;DR: It is suggested that stress sensitivity, aberrant salience, and threat anticipation are important psychological processes in the development of psychotic experiences in daily life in the early stages of the disorder.