U
Urs V. Berger
Researcher at Brigham and Women's Hospital
Publications - 44
Citations - 10003
Urs V. Berger is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: In situ hybridization & Glutamate receptor. The author has an hindex of 37, co-authored 44 publications receiving 9604 citations. Previous affiliations of Urs V. Berger include Beth Israel Deaconess Medical Center & Harvard University.
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Journal ArticleDOI
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
Hiromi Gunshin,Bryan Mackenzie,Urs V. Berger,Yoshimi Gunshin,Michael F. Romero,Walter F. Boron,Stephan Nussberger,John L. Gollan,Matthias A. Hediger +8 more
TL;DR: A new metal-ion transporter in the rat, DCT1, which has an unusually broad substrate range that includes Fe2+, Zn2+, Mn2+, Co2+, Cd2+, Cu2+, Ni2+ and Pb2+.
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LNA-mediated microRNA silencing in non-human primates
Joacim Elmén,Morten Lindow,Sylvia Schütz,Matthew Lawrence,Andreas Petri,Susanna Obad,Marie Lindholm,Maj Hedtjärn,Henrik Frydenlund Hansen,Urs V. Berger,Steven R. Gullans,Phil Kearney,Peter Sarnow,Ellen Marie Straarup,Sakari Kauppinen,Sakari Kauppinen +15 more
TL;DR: The utility of systemically administered LNA-antimiRs in exploring miRNA function in rodents and primates is demonstrated, and the potential of these compounds as a new class of therapeutics for disease-associated miRNAs is supported.
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A family of mammalian Na + -dependent L -ascorbic acid transporters
Hiroyasu Tsukaguchi,Taro Tokui,Bryan Mackenzie,Urs V. Berger,Xing-Zhen Chen,Yangxi Wang,Richard F. Brubaker,Matthias A. Hediger,Matthias A. Hediger +8 more
TL;DR: It is found that SVCT1 and SVCT2 each mediate concentrative, high-affinity L-ascorbic acid transport that is stereospecific and is driven by the Na+ electrochemical gradient.
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Molecular Cloning and Characterization of a Channel-like Transporter Mediating Intestinal Calcium Absorption
Ji-Bin Peng,Xing-Zhen Chen,Urs V. Berger,Peter M. Vassilev,Hiroyasu Tsukaguchi,Edward M. Brown,Matthias A. Hediger +6 more
TL;DR: The properties of a calcium transport protein (CaT1) cloned from rat duodenum using an expression cloning strategy in Xenopus laevis oocytes are reported, which likely plays a key role in the intestinal uptake of calcium.
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Molecular Characterization of a Broad Selectivity Neutral Solute Channel
Hiroyasu Tsukaguchi,Chairat Shayakul,Urs V. Berger,Bryan Mackenzie,Sreenivas Devidas,William B. Guggino,Alfred N. Van Hoek,Matthias A. Hediger +7 more
TL;DR: The expression cloning of a liver cDNA encoding a unique promiscuous solute channel (AQP9) that confers high permeability for both solute and water is reported, defining a new evolutionary branch of the major intrinsic protein family of aquaporin proteins and describing a previously unknown mechanism by which a large variety of solutes and water can pass through a single pore.