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V. Ashutosh Rao

Researcher at Center for Drug Evaluation and Research

Publications -  64
Citations -  13294

V. Ashutosh Rao is an academic researcher from Center for Drug Evaluation and Research. The author has contributed to research in topics: Medicine & DNA repair. The author has an hindex of 26, co-authored 50 publications receiving 11533 citations. Previous affiliations of V. Ashutosh Rao include St. Jude Children's Research Hospital & National Institutes of Health.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Gain of Function of a p53 Hot Spot Mutation in a Mouse Model of Li-Fraumeni Syndrome

Gene A. Lang, +11 more
- 17 Dec 2004 - 
TL;DR: In vivo validation for the gain-of-function properties of certain p53 missense mutations are provided and a mechanistic basis for these phenotypes is suggested.
Journal ArticleDOI

Repair of and checkpoint response to topoisomerase I-mediated DNA damage.

Yves Pommier, +11 more
- 27 Nov 2003 - 
TL;DR: Defects in these repair/checkpoint pathways, which promote tumor development, explain the selectivity of camptothecins and other Top1 inhibitors for cancer cells.
Book ChapterDOI

Repair of topoisomerase I-mediated DNA damage.

Yves Pommier, +24 more
- 01 Jan 2006 - 
TL;DR: This chapter reviews the developments in several pathways involved in the repair of Top1 cleavage complexes and the role of Chk1 and Chk2 checkpoint kinases in the cellular responses to Top1 inhibitors.