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Vani Pariyadath

Bio: Vani Pariyadath is an academic researcher from National Institute on Drug Abuse. The author has contributed to research in topics: Time perception & Illusion. The author has an hindex of 13, co-authored 22 publications receiving 1372 citations. Previous affiliations of Vani Pariyadath include National Institutes of Health & Allahabad University.

Papers
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Journal ArticleDOI
Donald J. Hagler1, Sean N. Hatton1, M. Daniela Cornejo1, Carolina Makowski2, Damien A. Fair3, Anthony Steven Dick4, Matthew T. Sutherland4, B. J. Casey5, M Deanna6, Michael P. Harms6, Richard Watts5, James M. Bjork7, Hugh Garavan8, Laura Hilmer1, Christopher J. Pung1, Chelsea S. Sicat1, Joshua M. Kuperman1, Hauke Bartsch1, Feng Xue1, Mary M. Heitzeg9, Angela R. Laird4, Thanh T. Trinh1, Raul Gonzalez4, Susan F. Tapert1, Michael C. Riedel4, Lindsay M. Squeglia10, Luke W. Hyde9, Monica D. Rosenberg5, Eric Earl3, Katia D. Howlett11, Fiona C. Baker12, Mary E. Soules9, Jazmin Diaz1, Octavio Ruiz de Leon1, Wesley K. Thompson1, Michael C. Neale7, Megan M. Herting13, Elizabeth R. Sowell13, Ruben P. Alvarez11, Samuel W. Hawes4, Mariana Sanchez4, Jerzy Bodurka14, Florence J. Breslin14, Amanda Sheffield Morris14, Martin P. Paulus14, W. Kyle Simmons14, Jonathan R. Polimeni15, Andre van der Kouwe15, Andrew S. Nencka16, Kevin M. Gray10, Carlo Pierpaoli11, John A. Matochik11, Antonio Noronha11, Will M. Aklin11, Kevin P. Conway11, Meyer D. Glantz11, Elizabeth Hoffman11, Roger Little11, Marsha F. Lopez11, Vani Pariyadath11, Susan R.B. Weiss11, Dana L. Wolff-Hughes, Rebecca DelCarmen-Wiggins, Sarah W. Feldstein Ewing3, Oscar Miranda-Dominguez3, Bonnie J. Nagel3, Anders Perrone3, Darrick Sturgeon3, Aimee Goldstone12, Adolf Pfefferbaum12, Kilian M. Pohl12, Devin Prouty12, Kristina A. Uban17, Susan Y. Bookheimer18, Mirella Dapretto18, Adriana Galván18, Kara Bagot1, Jay N. Giedd1, M. Alejandra Infante1, Joanna Jacobus1, Kevin Patrick1, Paul D. Shilling1, Rahul S. Desikan19, Yi Li19, Leo P. Sugrue19, Marie T. Banich20, Naomi P. Friedman20, John K. Hewitt20, Christian J. Hopfer20, Joseph T. Sakai20, Jody Tanabe20, Linda B. Cottler21, Sara Jo Nixon21, Linda Chang22, Christine C. Cloak22, Thomas Ernst22, Gloria Reeves22, David N. Kennedy23, Steve Heeringa9, Scott Peltier9, John E. Schulenberg9, Chandra Sripada9, Robert A. Zucker9, William G. Iacono24, Monica Luciana24, Finnegan J. Calabro25, Duncan B. Clark25, David A. Lewis25, Beatriz Luna25, Claudiu Schirda25, Tufikameni Brima26, John J. Foxe26, Edward G. Freedman26, Daniel W. Mruzek26, Michael J. Mason27, Rebekah S. Huber28, Erin McGlade28, Andrew P. Prescot28, Perry F. Renshaw28, Deborah A. Yurgelun-Todd28, Nicholas Allgaier8, Julie A. Dumas8, Masha Y. Ivanova8, Alexandra Potter8, Paul Florsheim29, Christine L. Larson29, Krista M. Lisdahl29, Michael E. Charness30, Michael E. Charness15, Michael E. Charness31, Bernard F. Fuemmeler7, John M. Hettema7, Hermine H. Maes7, Joel L. Steinberg7, Andrey P. Anokhin6, Paul E.A. Glaser6, Andrew C. Heath6, Pamela A. F. Madden6, Arielle R. Baskin-Sommers5, R. Todd Constable5, Steven Grant11, Gayathri J. Dowling11, Sandra A. Brown1, Terry L. Jernigan1, Anders M. Dale1 
TL;DR: The baseline neuroimaging processing and subject-level analysis methods used by the Adolescent Brain Cognitive Development Study are described to be a resource of unprecedented scale and depth for studying typical and atypical development.

431 citations

Journal ArticleDOI
TL;DR: It is suggested that a better understanding of how the insula modulates the interaction between these networks is critical for elucidating both the cognitive impairments often associated with withdrawal and the performance-enhancing effects of nicotine administration.

411 citations

Posted ContentDOI
Donald J. Hagler1, Sean N. Hatton1, Carolina Makowski2, M. Daniela Cornejo3, Damien A. Fair3, Anthony Steven Dick4, Matthew T. Sutherland4, B. J. Casey5, M Deanna6, Michael P. Harms6, Richard Watts5, James M. Bjork7, Hugh Garavan8, Laura Hilmer1, Christopher J. Pung1, Chelsea S. Sicat1, Joshua M. Kuperman1, Hauke Bartsch1, Feng Xue1, Mary M. Heitzeg9, Angela R. Laird4, Thanh T. Trinh1, Raul Gonzalez4, Susan F. Tapert1, Michael C. Riedel4, Lindsay M. Squeglia10, Luke W. Hyde9, Monica D. Rosenberg5, Eric Earl3, Katia D. Howlett11, Fiona C. Baker12, Mary E. Soules9, Jazmin Diaz1, Octavio Ruiz de Leon1, Wesley K. Thompson1, Michael C. Neale7, Megan M. Herting13, Elizabeth R. Sowell13, Ruben P. Alvarez14, Samuel W. Hawes4, Mariana Sanchez4, Jerzy Bodurka15, Florence J. Breslin15, Amanda Sheffield Morris15, Martin P. Paulus15, W. Kyle Simmons15, Jonathan R. Polimeni16, Andre van der Kouwe16, Andrew S. Nencka17, Kevin M. Gray10, Carlo Pierpaoli14, John A. Matochik14, Antonio Noronha14, Will M. Aklin11, Kevin P. Conway11, Meyer D. Glantz11, Elizabeth Hoffman11, Roger Little11, Marsha F. Lopez11, Vani Pariyadath11, Susan R.B. Weiss11, Dana L. Wolff-Hughes, Rebecca DelCarmen-Wiggins, Sarah W. Feldstein Ewing3, Oscar Miranda-Dominguez3, Bonnie J. Nagel3, Anders Perrone3, Darrick Sturgeon3, Aimee Goldstone12, Adolf Pfefferbaum12, Kilian M. Pohl12, Devin Prouty12, Kristina A. Uban1, Susan Y. Bookheimer1, Mirella Dapretto1, Adriana Galván1, Kara Bagot1, Jay N. Giedd1, M. Alejandra Infante1, Joanna Jacobus1, Kevin Patrick1, Paul D. Shilling1, Rahul S. Desikan1, Yi Li1, Leo P. Sugrue1, Marie T. Banich18, Naomi P. Friedman18, John K. Hewitt18, Christian J. Hopfer18, Joseph T. Sakai18, Jody Tanabe18, Linda B. Cottler19, Sara Jo Nixon19, Linda Chang20, Christine C. Cloak20, Thomas Ernst20, Gloria Reeves20, David N. Kennedy21, Steve Heeringa9, Scott Peltier9, John E. Schulenberg9, Chandra Sripada9, Robert A. Zucker9, William G. Iacono22, Monica Luciana22, Finnegan J. Calabro23, Duncan B. Clark23, David A. Lewis23, Beatriz Luna23, Claudiu Schirda23, Tufikameni Brima24, John J. Foxe24, Edward G. Freedman24, Daniel W. Mruzek24, Michael J. Mason25, Rebekah S. Huber26, Erin McGlade26, Andrew P. Prescot26, Perry F. Renshaw26, Deborah A. Yurgelun-Todd26, Nicholas Allgaier8, Julie A. Dumas8, Masha Y. Ivanova8, Alexandra Potter8, Paul Florsheim27, Christine L. Larson27, Krista M. Lisdahl27, Michael E. Charness28, Bernard F. Fuemmeler7, John M. Hettema7, Joel L. Steinberg7, Andrey P. Anokhin6, Paul E.A. Glaser6, Andrew C. Heath6, Pamela A. F. Madden6, Arielle R. Baskin-Sommers5, R. Todd Constable5, Steven Grant11, Gayathri J. Dowling11, Sandra A. Brown1, Terry L. Jernigan1, Anders M. Dale1 
04 Nov 2018-bioRxiv
TL;DR: The baseline neuroimaging processing and subject-level analysis methods used by the ABCD DAIC in the centralized processing and extraction of neuroanatomical and functional imaging phenotypes are described.
Abstract: The Adolescent Brain Cognitive Development (ABCD) Study is an ongoing, nationwide study of the effects of environmental influences on behavioral and brain development in adolescents. The ABCD Study is a collaborative effort, including a Coordinating Center, 21 data acquisition sites across the United States, and a Data Analysis and Informatics Center (DAIC). The main objective of the study is to recruit and assess over eleven thousand 9-10-year-olds and follow them over the course of 10 years to characterize normative brain and cognitive development, the many factors that influence brain development, and the effects of those factors on mental health and other outcomes. The study employs state-of-the-art multimodal brain imaging, cognitive and clinical assessments, bioassays, and careful assessment of substance use, environment, psychopathological symptoms, and social functioning. The data will provide a resource of unprecedented scale and depth for studying typical and atypical development. Here, we describe the baseline neuroimaging processing and subject-level analysis methods used by the ABCD DAIC in the centralized processing and extraction of neuroanatomical and functional imaging phenotypes. Neuroimaging processing and analyses include modality-specific corrections for distortions and motion, brain segmentation and cortical surface reconstruction derived from structural magnetic resonance imaging (sMRI), analysis of brain microstructure using diffusion MRI (dMRI), task-related analysis of functional MRI (fMRI), and functional connectivity analysis of resting-state fMRI.

276 citations

Journal ArticleDOI
28 Nov 2007-PLOS ONE
TL;DR: It is shown that when a sound or visual flickers is presented in conjunction with an unexpected visual stimulus, neither the pitch of the sound nor the frequency of the flicker is affected by the apparent duration dilation, demonstrating that subjective time in general is not slowed; instead, duration judgments can be manipulated with no concurrent impact on other temporal judgments.
Abstract: Events can sometimes appear longer or shorter in duration than other events of equal length. For example, in a repeated presentation of auditory or visual stimuli, an unexpected object of equivalent duration appears to last longer. Illusions of duration distortion beg an important question of time representation: when durations dilate or contract, does time in general slow down or speed up during that moment? In other words, what entailments do duration distortions have with respect to other timing judgments? We here show that when a sound or visual flicker is presented in conjunction with an unexpected visual stimulus, neither the pitch of the sound nor the frequency of the flicker is affected by the apparent duration dilation. This demonstrates that subjective time in general is not slowed; instead, duration judgments can be manipulated with no concurrent impact on other temporal judgments. Like spatial vision, time perception appears to be underpinned by a collaboration of separate neural mechanisms that usually work in concert but are separable. We further show that the duration dilation of an unexpected stimulus is not enhanced by increasing its saliency, suggesting that the effect is more closely related to prediction violation than enhanced attention. Finally, duration distortions induced by violations of progressive number sequences implicate the involvement of high-level predictability, suggesting the involvement of areas higher than primary visual cortex. We suggest that duration distortions can be understood in terms of repetition suppression, in which neural responses to repeated stimuli are diminished.

242 citations

Journal ArticleDOI
TL;DR: In this article, the authors suggest that the experience of duration is a signature of the amount of energy expended in representing a stimulus, i.e., the coding efficiency of a stimulus.
Abstract: Perceived duration is conventionally assumed to correspond with objective duration, but a growing literature suggests a more complex picture. For example, repeated stimuli appear briefer in duration than a novel stimulus of equal physical duration. We suggest that such duration illusions appear to parallel the neural phenomenon of repetition suppression, and we marshal evidence for a new hypothesis: the experience of duration is a signature of the amount of energy expended in representing a stimulus, i.e. the coding efficiency. This novel hypothesis offers a unified explanation for almost a dozen illusions in the literature in which subjective duration is modulated by properties of the stimulus such as size, brightness, motion and rate of flicker.

209 citations


Cited by
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28 Jul 2005
TL;DR: PfPMP1)与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作�ly.
Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1(PfPMP1)与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员,通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

18,940 citations

Journal ArticleDOI
TL;DR: The logic and rationale behind the development of the behavioral, individual difference, and tfMRI batteries are described and preliminary data on the patterns of activation associated with each of the fMRI tasks are provided, at both group and individual levels.

1,271 citations

Journal ArticleDOI
Simon Grondin1
TL;DR: The present review article discusses the question of whether there is an internal clock (pacemaker counter or oscillator device) that is dedicated to temporal processing and reports the main hypotheses regarding the involvement of biological structures in time perception.
Abstract: The aim of the present review article is to guide the reader through portions of the human time perception, or temporal processing, literature. After distinguishing the main contemporary issues related to time perception, the article focuses on the main findings and explanations that are available in the literature on explicit judgments about temporal intervals. The review emphasizes studies that are concerned with the processing of intervals lasting a few milliseconds to several seconds and covers studies issuing from either a behavioral or a neuroscience approach. It also discusses the question of whether there is an internal clock (pacemaker counter or oscillator device) that is dedicated to temporal processing and reports the main hypotheses regarding the involvement of biological structures in time perception.

763 citations

01 Jan 2010
TL;DR: A review of recent literature related to psychological time and time perception can be found in this article, where the roles of the cerebellum, of the cerebral cortices, and of the basal ganglia in the timing processes are emphasized.
Abstract: Suppose someone had to prepare a review article on visual perception, instead of time perception. This individual would probably ask for a series of reviews, with at least one—and probably several—dedicated to color, distance, shape, and motion perception, and maybe to other aspects of visual perception. It would be very difficult to complete the same exercise for time perception since the categories of temporal experiences are not as clearly defined. However, for a reader to understand the scope of a text on time perception, it is essential to develop a representation of what the main research avenues or categories are. The present text should help the reader to grasp the scope of recent literature related to psychological time and time perception. After a brief overview of the various perspectives on what could be meant by psychological time, the review will propose to identify of series of key concepts and empirical findings that should delineate the field of time perception and timing, and will discuss some models of time perception. The article also provides a review of the main recent findings in the field in which a neuroscientific approach to timing is adopted. In this section, the roles of the cerebellum, of the cerebral cortices, and of the basal ganglia in the timing processes are emphasized. Time Perception Beyond the Focus of the Present Review

667 citations

Journal ArticleDOI
TL;DR: In this article , the authors used three of the largest neuroimaging datasets currently available, with a total sample size of around 50,000 individuals, to quantify brain-wide association studies effect sizes and reproducibility as a function of sample size.
Abstract: Magnetic resonance imaging (MRI) has transformed our understanding of the human brain through well-replicated mapping of abilities to specific structures (for example, lesion studies) and functions1-3 (for example, task functional MRI (fMRI)). Mental health research and care have yet to realize similar advances from MRI. A primary challenge has been replicating associations between inter-individual differences in brain structure or function and complex cognitive or mental health phenotypes (brain-wide association studies (BWAS)). Such BWAS have typically relied on sample sizes appropriate for classical brain mapping4 (the median neuroimaging study sample size is about 25), but potentially too small for capturing reproducible brain-behavioural phenotype associations5,6. Here we used three of the largest neuroimaging datasets currently available-with a total sample size of around 50,000 individuals-to quantify BWAS effect sizes and reproducibility as a function of sample size. BWAS associations were smaller than previously thought, resulting in statistically underpowered studies, inflated effect sizes and replication failures at typical sample sizes. As sample sizes grew into the thousands, replication rates began to improve and effect size inflation decreased. More robust BWAS effects were detected for functional MRI (versus structural), cognitive tests (versus mental health questionnaires) and multivariate methods (versus univariate). Smaller than expected brain-phenotype associations and variability across population subsamples can explain widespread BWAS replication failures. In contrast to non-BWAS approaches with larger effects (for example, lesions, interventions and within-person), BWAS reproducibility requires samples with thousands of individuals.

611 citations