Veena Kumari

TL;DR: It is hypothesized that Asperger's syndrome is associated with abnormalities in fronto-striatal pathways resulting in defective sensorimotor gating, and consequently characteristic difficulties inhibiting repetitive thoughts, speech and actions.

TL;DR: An overview of the explanations for elevated rates of smoking in schizophrenia is presented, with particular emphasis on the theories relating this behaviour to sensory gating and cognitive deficits in this disorder that have been viewed as major support for the self-medication hypotheses.

TL;DR: A review of studies attempting to determine the relationship between brain structure and neurocognition in schizophrenia revealed that whole brain volume tends to correlate with the measures of general intelligence as well as with a range of specific cognitive functions in normal controls and female schizophrenia patients, but this relationship is disrupted in male patients.

TL;DR: Clozapine is superior to typical antipsychotics in normalizing prepulse inhibition, presumably because of its pharmacological effects on prefrontal regions of the brain or its effects on a broader range of neuroreceptors.

TL;DR: The results are encouraging for multi-centre DTI studies in larger populations, but also illustrate the importance of the image processing pipeline for reproducibility.