Catalytic dehydrogenative cross-coupling: forming carbon-carbon bonds by oxidizing two carbon-hydrogen bonds

The direct functionalization of C-H bonds in organic compounds has recently emerged as a powerful and ideal method for the formation of carbon-carbon and carbon-heteroatom bonds. This Review provides an overview of C-H bond functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets.

C-H bond functionalization: emerging synthetic tools for natural products and pharmaceuticals

What makes organizations so similar? We contend that the engine of rationalization and bureaucratization has moved from the competitive marketplace to the state and the professions. Once a set of organizations emerges as a field, a paradox arises: rational actors make their organizations increasingly similar as they try to change them. We describe three isomorphic processes-coercive, mimetic, and normative—leading to this outcome. We then specify hypotheses about the impact of resource centralization and dependency, goal ambiguity and technical uncertainty, and professionalization and structuration on isomorphic change. Finally, we suggest implications for theories of organizations and social change.

The iron cage revisited: Institutional isomorphism and collective rationality in organizational fields (Chinese Translation)

https://www.pnas.org/content/pnas/90/5/1635.full.pdf

Supramolecular chemistry.

Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids

Advances in the chemistry of tetrahydroquinolines.

Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, being widespread in nature and present in a broad variety of pharmacologically active compounds. This Review summarizes the progress achieved in the chemistry of tetrahydroquinolines, with emphasis on their synthesis, during the period from mid-2010 to early 2018.

Progress in the Chemistry of Tetrahydroquinolines.

Cerium(IV) Ammonium Nitrate as a Catalyst in Organic Synthesis

A new three-component domino synthesis of 1,4-dihydropyridines

The use of cerium(IV) ammonium nitrate as a catalyst of the Friedlander reaction allows the synthesis of polysubstituted quinoline derivatives in excellent yields, avoiding the traditional harshly basic or acidic conditions. Unlike most other previously known reagents, CAN allows double condensations and is also an excellent catalyst for the Borsche variation of the Friedlander reaction, which has been applied to the very efficient synthesis of the antitumor alkaloid luotonin A.

Cerium(IV) Ammonium Nitrate Is an Excellent, General Catalyst for the Friedländer and Friedländer−Borsche Quinoline Syntheses: Very Efficient Access to the Antitumor Alkaloid Luotonin A

Vellaisamy Sridharan

Papers

Advances in the chemistry of tetrahydroquinolines.

Progress in the Chemistry of Tetrahydroquinolines.

Cerium(IV) Ammonium Nitrate as a Catalyst in Organic Synthesis

A new three-component domino synthesis of 1,4-dihydropyridines

Cerium(IV) Ammonium Nitrate Is an Excellent, General Catalyst for the Friedländer and Friedländer−Borsche Quinoline Syntheses: Very Efficient Access to the Antitumor Alkaloid Luotonin A