Victor C. Yang

TL;DR: The folic acid-conjugated microspheres may be a promising vector for delivery of anti-cancer drugs as it exhibits a low cytotoxicity and degradability, precise molecular targeting property and multi-stimuli responsively controlled drug release.

TL;DR: Scaffold-supported combined administration of synMSCs with BMP-7 resulted in high proteoglycan and collagen type II induction and thick hyaline cartilage formation and intra-articular co-delivery of synSCs with BMCs via fibrous PLGA scaffolds may be a promising therapeutic modality for articular cartilage repair.

TL;DR: Two steroidal glycosides named riparoside B and timosaponin J are found to possess potent uricosuric effect in hyperuricemic mice through decreasing renal mURAT1 mainly and inhibiting XOD activity in a certain extent, which contribute to the enhancement of uric acid excretion and attenuatehyperuricemia-induced renal dysfunction.

TL;DR: It is demonstrated, both in vitro and in vivo, that the cell transduction of TAT-Gel can be completely curbed with heparin and yet thisHeparin block can be efficiently reversed by the addition of protamine.

TL;DR: In this paper, a target activated cell/tissue translocation peptide for an impermeable compound strategy (TACTICS), which comprises (a) a protein transport domain (PTD), (b) a masking domain, and (c) a spacer having a target cell-tissue enzyme-specific cleavage, was presented.