Victoria Alexandra Steadman

TL;DR: The properties of this compound suggest a path towards developing antibiotics that are likely to avoid development of resistance, as well as several methods to grow uncultured organisms by cultivation in situ or by using specific growth factors.

TL;DR: In this article, compounds of Formula I: and pharmaceutically acceptable salts and esters thereof are provided for the treatment of virus infections, particularly hepatitis C infections. But none of these compounds are suitable for the use in medical applications.

TL;DR: The synthetic accessibility and properties of cyclophilin inhibitor support its potential as an anti-HCV agent and for interrogating the role of Cyp inhibition in a variety of diseases.

TL;DR: This corrects the article to show that the Higgs boson genome is a “spatially aggregated “vessel” rather than an “ aggregating “ nucleus”, which indicates that theorems related to “consolidation” and “ghosting” are more likely to occur.

TL;DR: Replacing the C18-C21 diene unit of sanglifehrin with a styryl group led to potent compounds that displayed a novel binding mode in which the styrene moiety engaged in a π-stacking interaction with Arg55 of cyclophilin A (Cyp A), and the m-Tyr residue was displaced into solvent.