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Vinay Puri

Researcher at University College London

Publications -  24
Citations -  11317

Vinay Puri is an academic researcher from University College London. The author has contributed to research in topics: Genetic association & Linkage disequilibrium. The author has an hindex of 20, co-authored 24 publications receiving 10315 citations.

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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

Shaun Purcell, +81 more
- 06 Aug 2009 - 
TL;DR: The extent to which common genetic variation underlies the risk of schizophrenia is shown, using two analytic approaches, and the major histocompatibility complex is implicate, which is shown to involve thousands of common alleles of very small effect.
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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

S. Hong Lee, +405 more
- 01 Sep 2013 - 
TL;DR: Empirical evidence of shared genetic etiology for psychiatric disorders can inform nosology and encourages the investigation of common pathophysiologies for related disorders.
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Genome-wide association study identifies five new schizophrenia loci

Stephan Ripke, +210 more
- 01 Oct 2011 - 
TL;DR: The authors examined the role of common genetic variation in schizophrenia in a genome-wide association study of substantial size: a stage 1 discovery sample of 21,856 individuals of European ancestry and a stage 2 replication sample of 29,839 independent subjects.
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Rare chromosomal deletions and duplications increase risk of schizophrenia

Jennifer Stone, +91 more
- 11 Sep 2008 - 
TL;DR: A genome-wide survey of rare CNVs in 3,391 patients with schizophrenia and 3,181 ancestrally matched controls provides strong support for a model of schizophrenia pathogenesis that includes the effects of multiple rare structural variants, both genome- wide and at specific loci.
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Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Colm O'Dushlaine, +404 more
- 19 Jan 2015 - 
TL;DR: It is indicated that risk variants for psychiatric disorders aggregate in particular biological pathways and that these pathways are frequently shared between disorders.