Virgil Radu Enatescu

TL;DR: The miRWalk analysis of changes in plasma microRNAs after treatment of patients with major depression might open a new avenue for the understanding of Escitalopram mode of action and for its side effects.

TL;DR: Different dimensions of personality may play a contributing role in the development of suicide ideation in perinatal women, and personality dimensions and trait anxiety, not only depressive symptoms, should be investigated when attempting to identify per inatal women at risk of suicide.

TL;DR: Coping styles in patients with COPD affect the intensity of associated depressive and anxiety symptoms as well as medical determinants, thus the coping style should be considered an important part in the multidisciplinary approach of these patients.

TL;DR: The significant correlations between the CYP polymorphisms for group G2 (without pharmacogenetic testing) and the weight gain/body mass index (BMI) increase, as major side effects induced by antidepressants, proved the fact that the pharmacogenetics screening is needed in the future clinical practice, allowing for individualized, tailored treatment, especially for at-risk pediatric categories.

TL;DR: In this article, an untargeted metabolomic profiling performed in plasma samples of 11 major depressive disorder patients, at baseline and at 12 weeks following antidepressant therapy with escitalopram (MDD2), and in 11 healthy controls (C), using ultra-high performance liquid chromatography coupled with electrospray ionization-quadrupole-time of flight-mass spectrometry (UHPLC-QTOF-(ESI+)-MS).