Vitalij Novickij

TL;DR: In this article, a novel electroporator which is capable of generating single and bursts of high power (3,kV, 60 A) square wave pulses of variable duration (100 ns to 1 ms) with predefined repetition frequency (1 Hz to 3.5 MHz).

TL;DR: The cytotoxic efficiency showed no apparent correlation with cell or nuclear size, cell morphology, metabolism level, or the extent of membrane disruption by ns PEF, suggesting that manipulation of PEF parameters can, at least for certain cancers, overcome their resistance to nsPEF ablation.

TL;DR: It was shown that the PRF is an important parameter that could be used for flexible control of electroporation efficiency in the high frequency range and it was determined that a threshold PRF exists when the relaxation of the cell transmembrane potential is longer than the delay between the consequent pulses.

TL;DR: This work shows how temporal summation when pulses are compressed into high-rate bursts is a universal and efficient way to lower excitation thresholds and facilitate electroporation.

TL;DR: Results show increased membrane permeability by PEF when combined with magnetic field pulse, which can explain electroporation at considerably lower electric field strengths induced by PEMF compared to classical Electroporation.