Author
Vitomir Šunjić
Other affiliations: GlaxoSmithKline
Bio: Vitomir Šunjić is an academic researcher from University of Zagreb. The author has contributed to research in topics: Enantioselective synthesis & Stereoselectivity. The author has an hindex of 22, co-authored 191 publications receiving 2030 citations. Previous affiliations of Vitomir Šunjić include GlaxoSmithKline.
Papers published on a yearly basis
Papers
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174 citations
130 citations
TL;DR: In this paper, pure trans-(R, R )-diaryl-epoxides are obtained in two steps and under aprotic conditions using Eliel's oxathiane as the chiral auxiliary.
Abstract: Pure trans -( R , R )-diaryl-epoxides are obtained in two steps and under aprotic conditions using Eliel's oxathiane as the chiral auxiliary. The enantiomeric excesses, determined by chiral HPLC, are 97.9% to 99.9% and the oxathiane is recovered in 78% to 92% yield and may thus be re-used.
58 citations
TL;DR: Combining circular dichroism and gel filtration method in studying the binding of chiral ((S)/R)- 1 and prochiral benzodiazepines to human serum albumin (HSA) revealed that both enantiomers of 1 are bound by HSA with different affinities.
54 citations
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2,308 citations
TL;DR: In this paper, a thorough discussion of homogeneous catalysis by transition metal oxygen anion clusters (polyoxometalates), with a focus on mechanism, is provided, and a general compilation of the reactions, including catalytic electrooxidations or electroreductions, reported to date is given.
1,331 citations
TL;DR: An overview of the wide range of nanoreactors that have been constructed from synthetic and biological building blocks using both covalent and noncovalent approaches is given, starting from small organic molecular containers expanding to large compartment-containing assemblies.
Abstract: An overview of the wide range of nanoreactors that have been constructed from synthetic and biological building blocks using both covalent and noncovalent approaches is given. Focus is on self-assembled systems, varying in size from a few nanometers to tens of micrometers. The review is divided into several sections that cover the development of tailor-made nanoreactors, starting from small organic molecular containers expanding to large compartment-containing assemblies. First, the construction of capsules from low molecular weight compounds by means of covalent synthesis and self-assembly by highly directive and pre-designed interactions is discussed. Second, nanocapsules based on micellar and vesicular assemblies that are built up frow low molecular weight molecules are described. Finally, the construction of nanoreactors from macromolecular building blocks, as well as recent developments in the use of viruses as nanocontainers and reactors are outlined.
1,297 citations
TL;DR: The discussion focuses on the application of ECD, also in combination with other methods, in structural analysis of organic compounds, including host-guest complexes, and will emphasize the importance of the interplay between configurational and conformational factors.
Abstract: This tutorial review is addressed to readers with a background in basic organic chemistry and spectroscopy, but without a specific knowledge of electronic circular dichroism. It describes the fundamental principles, instrumentation, data analysis, and different approaches for interpretation of ECD. The discussion focuses on the application of ECD, also in combination with other methods, in structural analysis of organic compounds, including host–guest complexes, and will emphasize the importance of the interplay between configurational and conformational factors. The tutorial also covers modern supramolecular aspects of ECD and recent developments in computational methods.
1,000 citations
995 citations