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Vladimir P. Torchilin

Researcher at Northeastern University

Publications -  644
Citations -  64673

Vladimir P. Torchilin is an academic researcher from Northeastern University. The author has contributed to research in topics: Liposome & Drug delivery. The author has an hindex of 109, co-authored 627 publications receiving 58977 citations. Previous affiliations of Vladimir P. Torchilin include College of Health Sciences, Bahrain & Rice University.

Papers
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Journal ArticleDOI

Recent advances with liposomes as pharmaceutical carriers.

Vladimir P. Torchilin
- 01 Feb 2005 - 
TL;DR: For further successful development of this field, promising trends must be identified and exploited, albeit with a clear understanding of the limitations of these approaches.
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Biodegradable long-circulating polymeric nanospheres

Ruxandra Gref, +5 more
- 18 Mar 1994 - 
TL;DR: Monodisperse biodegradable nanospheres were developed from amphiphilic copolymers composed of two biocompatible blocks and exhibited dramatically increased blood circulation times and reduced liver accumulation in mice.
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Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment

Susan K. Hobbs, +6 more
- 14 Apr 1998 - 
TL;DR: Delivery may be less efficient in cranial tumors than in subcutaneous tumors, delivery may be reduced during tumor regression induced by hormonal ablation, and permeability to a molecule is independent of pore cutoff size as long as the diameter of the molecule is much less than the pore diameter.
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Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

Alexander L. Klibanov, +3 more
- 30 Jul 1990 - 
TL;DR: The PEG‐PE's activity to prolong the circulation time of liposomes is greater than that of the ganglioside GM1, awell‐described glycolipid with this activity.
Journal Article

Vascular Permeability in a Human Tumor Xenograft: Molecular Size Dependence and Cutoff Size

Fan Yuan, +6 more
- 01 Sep 1995 - 
TL;DR: Tumor vessels in the model found that tumor vessels in this model were permeable to liposomes of up to 400 nm in diameter, suggesting that the cutoff size of the pores is between 400 and 600nm in diameter.