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Vyacheslav Ya. Sosnovskikh

Researcher at Ural Federal University

Publications -  365
Citations -  3365

Vyacheslav Ya. Sosnovskikh is an academic researcher from Ural Federal University. The author has contributed to research in topics: Trifluoromethyl & Cycloaddition. The author has an hindex of 25, co-authored 350 publications receiving 2892 citations. Previous affiliations of Vyacheslav Ya. Sosnovskikh include Russian Academy of Sciences & Enamine Ltd.

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Organofluorine chemistry: promising growth areas and challenges

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Synthesis and reactions of halogen-containing chromones

TL;DR: In this paper, published data on the synthesis and reactivity of halogen-containing chromones, flavones, thiochromones and furochromones are generalised.
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Regioselective nucleophilic 1,4-trifluoromethylation of 2-polyfluoroalkylchromones with (trifluoromethyl)trimethylsilane. Synthesis of fluorinated analogs of natural 2,2-dimethylchroman-4-ones and 2,2-dimethylchromenes.

TL;DR: Reduction of substituted 2,2-bis(trifluoromethyl)chroman-4-one with sodium borohydride in methanol and subsequent dehydration of chromanols in refluxing xylene in the presence of p-toluene sulfonic acid gives 2,4-nucleophilic perfluoroalkylation, which are fluorinated analogues of natural precocenes.
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Synthesis of 3‐substituted 2‐trifluoro(trichloro)methyl‐2H‐chromenes by reaction of salicylaldehydes with activated trihalomethyl alkenes

TL;DR: The reaction of activated trihalome- thylsubstituted alkenes with salicylaldehydes in the presence of triethylamine gives 3-substitized 2-trifluo- romethylchroman-4-ols and 2- trifluoro(trichloro)methyl-2H-chromenes in high yields.
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Regioselective 1,4-trifluoromethylation of α,β-enones using ‘protect-in-situ’ methodology

TL;DR: In this paper, the nucleophilic 1,4-trifluoromethylation of several α,β-enones using trifluorsilane was achieved.