W
W. Kelley Thomas
Researcher at University of New Hampshire
Publications - 138
Citations - 11834
W. Kelley Thomas is an academic researcher from University of New Hampshire. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 45, co-authored 128 publications receiving 10587 citations. Previous affiliations of W. Kelley Thomas include University of California, Berkeley & Durham University.
Papers
More filters
Journal ArticleDOI
A molecular evolutionary framework for the phylum Nematoda
Mark Blaxter,Paul De Ley,Paul De Ley,James R. Garey,Leo X. Liu,Patsy Scheldeman,Andy Vierstraete,Jacques R. Vanfleteren,Laura Y. Mackey,M. Dorris,Linda M. Frisse,J. T. Vida,W. Kelley Thomas +12 more
TL;DR: It is suggested that animal parasitism arose independently at least four times, and plant parasitism three times, which indicates that convergent morphological evolution may be extensive and that present higher-level classification of the Nematoda will need revision.
Journal ArticleDOI
The ecoresponsive genome of Daphnia pulex
John K. Colbourne,Michael E. Pfrender,Michael E. Pfrender,Donald L. Gilbert,W. Kelley Thomas,Abraham E. Tucker,Abraham E. Tucker,Todd H. Oakley,Shin-ichi Tokishita,Andrea Aerts,Georg J. Arnold,Malay Kumar Basu,Malay Kumar Basu,Darren J Bauer,Carla E. Cáceres,Liran Carmel,Liran Carmel,Claudio Casola,Jeong Hyeon Choi,John C. Detter,Qunfeng Dong,Qunfeng Dong,Serge Dusheyko,Brian D. Eads,Thomas Fröhlich,Kerry Geiler-Samerotte,Kerry Geiler-Samerotte,Daniel Gerlach,Daniel Gerlach,Phil Hatcher,Sanjuro Jogdeo,Sanjuro Jogdeo,Jeroen Krijgsveld,Evgenia V. Kriventseva,Dietmar Kültz,Christian Laforsch,Erika Lindquist,Jacqueline Lopez,J. Robert Manak,J. Robert Manak,Jean Muller,Jasmyn Pangilinan,Rupali P Patwardhan,Rupali P Patwardhan,Samuel Pitluck,Ellen J. Pritham,Andreas Rechtsteiner,Andreas Rechtsteiner,Mina Rho,Igor B. Rogozin,Onur Sakarya,Onur Sakarya,Asaf Salamov,Sarah Schaack,Sarah Schaack,Harris Shapiro,Yasuhiro Shiga,Courtney Skalitzky,Zachary Smith,Alexander Souvorov,Way Sung,Zuojian Tang,Zuojian Tang,Dai Tsuchiya,Hank Tu,Hank Tu,Harmjan R. Vos,Mei Wang,Yuri I. Wolf,Hideo Yamagata,Takuji Yamada,Yuzhen Ye,Joseph R. Shaw,Justen Andrews,Teresa J. Crease,Haixu Tang,Susan Lucas,Hugh M. Robertson,Peer Bork,Eugene V. Koonin,Evgeny M. Zdobnov,Evgeny M. Zdobnov,Igor V. Grigoriev,Michael Lynch,Jeffrey L. Boore,Jeffrey L. Boore +85 more
TL;DR: The Daphnia genome reveals a multitude of genes and shows adaptation through gene family expansions, and the coexpansion of gene families interacting within metabolic pathways suggests that the maintenance of duplicated genes is not random.
Journal ArticleDOI
A genome-wide view of the spectrum of spontaneous mutations in yeast
Michael Lynch,Way Sung,Krystalynne Morris,Nicole Coffey,Christian R. Landry,Christian R. Landry,Erik B. Dopman,W. Joseph Dickinson,Kazufusa Okamoto,Shilpa Kulkarni,Daniel L. Hartl,W. Kelley Thomas +11 more
TL;DR: The use of complete-genome sequencing in the characterization of spontaneously arising mutations in the yeast Saccharomyces cerevisiae yields numerous unexpected findings, in particular a very high rate of point mutation and skewed distribution of base-substitution types in the mitochondrion and segmental duplication and deletion in the nuclear genome.
Journal ArticleDOI
Genetic drift, selection and the evolution of the mutation rate
Michael Lynch,Matthew S. Ackerman,Jean-François Gout,Hongan Long,Way Sung,W. Kelley Thomas,Patricia L. Foster +6 more
TL;DR: This work concludes that the drift-barrier hypothesis is consistent with comparative measures of mutation rates, provides a simple explanation for the existence of error-prone polymerases and yields a formal counter-argument to the view that selection fine-tunes gene-specific mutation rates.
Journal ArticleDOI
Sequencing our way towards understanding global eukaryotic biodiversity
Holly M. Bik,Dorota L. Porazinska,Simon Creer,J. Gregory Caporaso,Rob Knight,Rob Knight,W. Kelley Thomas +6 more
TL;DR: Despite a promising outlook, the field of eukaryotic marker gene surveys faces significant challenges: how to generate data that are most useful to the community, especially in the face of evolving sequencing technologies and bioinformatics pipelines, and how to incorporate an expanding number of target genes.