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Wael Mamdouh

Researcher at American University in Cairo

Publications -  62
Citations -  4244

Wael Mamdouh is an academic researcher from American University in Cairo. The author has contributed to research in topics: Supramolecular chemistry & Chemistry. The author has an hindex of 22, co-authored 56 publications receiving 3646 citations. Previous affiliations of Wael Mamdouh include Max Planck Society & University of Groningen.

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Self-assembly of a nanoscale DNA box with a controllable lid.

TL;DR: The DNA origami method is extended into three dimensions by creating an addressable DNA box that can be opened in the presence of externally supplied DNA ‘keys’, and controlled access to the interior compartment of this DNA nanocontainer could yield several interesting applications.
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Single-molecule chemical reactions on DNA origami

TL;DR: It is shown that chemical reactions with single molecules can be performed and imaged at a local position on a DNA origami scaffold by atomic force microscopy and demonstrate the feasibility of post-assembly chemical modification of DNA nanostructures and their potential use as locally addressable solid supports.
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Two-dimensional porous molecular networks of dehydrobenzo[12]annulene derivatives via alkyl chain interdigitation.

TL;DR: The self-assembly of a series of hexadehydrotribenzo[12]annulene (DBA) derivatives has been scrutinized by scanning tunneling microscopy (STM) at the liquid-solid interface and the effect of alkyl chain length on the structure of DBA patterns was investigated.
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DNA Origami Design of Dolphin-Shaped Structures with Flexible Tails

TL;DR: A user-friendly software package for designing DNA origami structures is presented and it is shown that the addition of specific attachment sites promotes dimerization between two independently self-assembled dolphin structures, and that these interactions stabilize the flexible tail.
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Comparative study of encapsulated peppermint and green tea essential oils in chitosan nanoparticles: Encapsulation, thermal stability, in-vitro release, antioxidant and antibacterial activities.

TL;DR: The nano-encapsulation maintained the stability of the total phenolic contents in both EOs, improved the antioxidant activity by ~2 and 2.4-fold for PO and GTO respectively, and Surprisingly, the antibacterial activity of CS/GTO NPs was more potent than CS/PO NPs and especially against Staphylococcus aureus.