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Walter J. Gensler

Bio: Walter J. Gensler is an academic researcher. The author has contributed to research in topics: Podophyllotoxin & Polyunsaturated fatty acid. The author has an hindex of 18, co-authored 67 publications receiving 1026 citations.



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Journal ArticleDOI
TL;DR: This review deals with the historical discovery of particularly important lignan derivatives used in cancer chemotherapy, and it will be demonstrated how the activities and the ability of this class of compounds to inhibit topoisomerase II were discovered by different research teams.

333 citations

Journal ArticleDOI
TL;DR: The chain elongation described here can clearly be distinguished from synthesis de novo in the supernatant and from a proposed reversal of the mitochondrial β-oxidation.

278 citations

Journal ArticleDOI
TL;DR: In this paper, the scope and limitations of the conjugate addition of homochiral lithium amides to act as homochirionic ammonia equivalents for the asymmetric synthesis of a range of β-amino carboxylic acid derivatives and its widespread applications in synthesis are discussed.
Abstract: This review delineates the scope and limitations of the conjugate addition of homochiral lithium amides to act as homochiral ammonia equivalents for the asymmetric synthesis of a range of β-amino carboxylic acid derivatives and its widespread applications in synthesis.

248 citations