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Walter J. Kozumbo

Researcher at University of Massachusetts Amherst

Publications -  23
Citations -  1486

Walter J. Kozumbo is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Hormesis & DNA damage. The author has an hindex of 14, co-authored 23 publications receiving 1169 citations. Previous affiliations of Walter J. Kozumbo include University of North Carolina at Chapel Hill.

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Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework

Edward J. Calabrese, +57 more
TL;DR: This article offers a set of recommendations that scientists believe can achieve greater conceptual harmony in dose-response terminology, as well as better understanding and communication across the broad spectrum of biological disciplines.
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Estimating the range of the maximum hormetic stimulatory response.

TL;DR: A novel perspective for improving research protocols, unraveling the limits of biological plasticity, understanding low‐level stress biology, advancing human and ecological health, and enhancing human performance is offered.
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The hormetic dose-response mechanism: Nrf2 activation

TL;DR: A generalized mechanism for hormetic dose responses is proposed that is based on the redox-activated transcription factor (TF), Nrf2, and its upregulation of an integrative system of endogenous anti-oxidant and anti-inflammatory adaptive responses as discussed by the authors.
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Assessment of the mutagenicity of phthalate esters.

TL;DR: Both the mutagenicity and binding of DMP are inversely related to the metabolism of this compound, suggesting that skin could be at high risk for a mutagenic/carcinogenic insult.