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Wanderley de Souza

Researcher at Federal University of Rio de Janeiro

Publications -  582
Citations -  20886

Wanderley de Souza is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Trypanosoma cruzi & Toxoplasma gondii. The author has an hindex of 55, co-authored 557 publications receiving 18737 citations. Previous affiliations of Wanderley de Souza include Oswaldo Cruz Foundation & State University of Norte Fluminense.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Acidocalcisomes ? conserved from bacteria to man

TL;DR: Acidocalcisomes were first described in trypanosomatids and have been characterized in most detail in these species, and are linked with several functions, including storage of cations and phosphorus, polyphosphate metabolism, calciumHomeostasis, maintenance of intracellular pH homeostasis and osmoregulation.
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Review on Trypanosoma cruzi: Host Cell Interaction.

TL;DR: A brief review of the interaction between Trypanosoma cruzi and its host cells is presented, mainly emphasizing the mechanisms and molecules that participate in the T. cruzi invasion process of the mammalian cells.
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Basic cell biology of Trypanosoma cruzi.

TL;DR: Basic aspects of the biology of Trypanosoma cruzi are reviewed, including the cytoskeleton of the protozoan, especially the sub-pellicular microtubules, and the process of interaction of the parasite with host cells are reviewed.
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Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs.

TL;DR: The results show that the mitochondrial membrane as well as the membrane lining the protozoan cell body and flagellum are the main targets, and apoptosis-like and autophagic processes induced by several of the inhibitors tested led to parasite death.