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Wei Fu
Publications - 1
Citations - 56
Wei Fu is an academic researcher. The author has an hindex of 1, co-authored 1 publications receiving 51 citations.
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Design, synthesis, and biological evaluation of deuterated C-aryl glycoside as a potent and long-acting renal sodium-dependent glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes.
Ge Xu,Binhua Lv,Jacques Y. Roberge,Baihua Xu,Jiyan Du,Jiajia Dong,Yuanwei Chen,Kun Peng,Lili Zhang,Xinxing Tang,Yan Feng,Min Xu,Wei Fu,Wenbin Zhang,Liangcheng Zhu,Zhongping Deng,Zelin Sheng,Ajith Welihinda,Xun Sun +18 more
TL;DR: S GLT2 inhibitors deuterated at sites susceptible to oxidative metabolism were found to have a slightly longer tmax and half-life, dose-dependent increase in urinary glucose excretion in rats, and slightly superior effects on UGE in dogs while retaining similar in vitro inhibitory activities against hSGLT2.