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Wei Gu
Researcher at University of California, San Francisco
Publications - 50
Citations - 6469
Wei Gu is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Medicine & Multiplex. The author has an hindex of 25, co-authored 46 publications receiving 4352 citations. Previous affiliations of Wei Gu include University of California, Berkeley & University of Michigan.
Papers
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Journal ArticleDOI
CRISPR-Cas12-based detection of SARS-CoV-2.
James Paul Broughton,Xianding Deng,Guixia Yu,Clare L Fasching,Venice Servellita,Jasmeet Singh,Xin Miao,Jessica Streithorst,Andrea Granados,Alicia Sotomayor-Gonzalez,Kelsey C. Zorn,Allan Gopez,Elaine Hsu,Wei Gu,Steve Miller,Chao Yang Pan,Hugo Guevara,Debra A. Wadford,Janice S. Chen,Charles Y. Chiu +19 more
TL;DR: The CRISPR-based DETECTR assay provides a visual and faster alternative to the US Centers for Disease Control and Prevention SARS-CoV-2 real-time RT–PCR assay, with 95% positive predictive agreement and 100% negative predictive agreement.
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Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection.
TL;DR: This review focuses on the application of untargeted metagenomic next-generation sequencing to the clinical diagnosis of infectious diseases, particularly in areas in which conventional diagnostic approaches have limitations.
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Microfluidics for flow cytometric analysis of cells and particles.
TL;DR: This review describes recent developments in microfabricated flow cytometers and related microfluidic devices that can detect, analyze, and sort cells or particles and presents various efforts that take advantage of novel microscale flow phenomena and microFabrication techniques to build microfluidity cell analysis systems.
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Computerized microfluidic cell culture using elastomeric channels and Braille displays
TL;DR: This paper demonstrates how a refreshable Braille display, with its grid of 320 vertically moving pins, can power integrated pumps and valves through localized deformations of channel networks within elastic silicone rubber.
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Non-invasive prenatal measurement of the fetal genome
H. Christina Fan,Wei Gu,Jianbin Wang,Yair J. Blumenfeld,Yasser Y. El-Sayed,Stephen R. Quake,Stephen R. Quake +6 more
TL;DR: It is demonstrated that it is possible to non-invasively sequence the entire prenatal genome and molecular counting of parental haplotypes in maternal plasma by shotgun sequencing of maternal plasma DNA allows the inherited fetal genome to be deciphered non- invasively.