W
Weihong Tan
Researcher at Hunan University
Publications - 1018
Citations - 78699
Weihong Tan is an academic researcher from Hunan University. The author has contributed to research in topics: Aptamer & Medicine. The author has an hindex of 140, co-authored 892 publications receiving 67151 citations. Previous affiliations of Weihong Tan include University of Florida & McKnight Brain Institute.
Papers
More filters
Journal ArticleDOI
Aptamers evolved from live cells as effective molecular probes for cancer study
Dihua Shangguan,Ying Li,Zhiwen Tang,Zehui Charles Cao,Hui William Chen,Prabodhika Mallikaratchy,Kwame Sefah,Chaoyong James Yang,Weihong Tan +8 more
TL;DR: A group of aptamers have been generated for the specific recognition of leukemia cells that can specifically recognize target leukemia cells mixed with normal human bone marrow aspirates and can also identify cancer cells closely related to the target cell line in real clinical specimens.
Journal ArticleDOI
Surface modification of silica nanoparticles to reduce aggregation and nonspecific binding.
TL;DR: Using these surface-modification schemes, fluorescent dye-doped silica nanoparticles can be more readily conjugated with biomolecules and used as highly fluorescent, sensitive, and reproducible labels in bioanalytical applications.
Journal ArticleDOI
Synthesis and Characterization of Silica-Coated Iron Oxide Nanoparticles in Microemulsion: The Effect of Nonionic Surfactants
Swadeshmukul Santra,Rovelyn Tapec,Nikoleta Theodoropoulou,Jon Dobson,and Arthur Hebard,Weihong Tan +5 more
TL;DR: In this paper, a water-in-oil microemulsion method has been applied for the preparation of silica-coated iron oxide nanoparticles, and their effects on the particle size, crystallinity, and the magnetic properties have been studied.
Journal ArticleDOI
Conjugation of biomolecules with luminophore-doped silica nanoparticles for photostable biomarkers.
TL;DR: A new molecular conjugation method has been developed to label biomolecules with optically stable metalorganic luminophores, such as tris(2,2'-bipyridyl)dichlororuthenium(II) hexahydrate (Rubpy), which are otherwise not possible for direct linking with the biomolecule.
Journal ArticleDOI
Development of DNA aptamers using Cell-SELEX
Kwame Sefah,Dihua Shangguan,Dihua Shangguan,Xiangling Xiong,Meghan B. O’Donoghue,Weihong Tan,Weihong Tan +6 more
TL;DR: This protocol, cell-SELEX (systematic evolution of ligands by exponential enrichment), is a method that can generate DNA aptamers that can bind specifically to a cell type of interest.