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Weiping Su
Researcher at Oregon National Primate Research Center
Publications - 15
Citations - 521
Weiping Su is an academic researcher from Oregon National Primate Research Center. The author has contributed to research in topics: Neural stem cell & Hippocampal formation. The author has an hindex of 11, co-authored 14 publications receiving 428 citations.
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Journal ArticleDOI
Digestion products of the PH20 hyaluronidase inhibit remyelination.
Marnie A. Preston,Xi Gong,Weiping Su,S. G. Matsumoto,Fatima Banine,Clayton W. Winkler,Scott Foster,Rubing Xing,Jaime Struve,Justin M. Dean,Bruce A. Baggenstoss,Paul H. Weigel,Thomas J. Montine,Stephen A. Back,Larry S. Sherman +14 more
TL;DR: It is tested the hypothesis that OPCs in demyelinating lesions express a specific hyaluronidase, and that digestion products of this enzyme inhibit OPC maturation.
Journal ArticleDOI
Astrocytes in aged nonhuman primate brain gray matter synthesize excess hyaluronan
Robert Cargill,Steven G. Kohama,Jaime Struve,Weiping Su,Fatima Banine,Ellen Witkowski,Stephen A. Back,Larry S. Sherman +7 more
TL;DR: It is found that HA levels significantly increase with age in the gray matter of rhesus macaques, and data indicate that HAS1 and CD44 are transcriptionally upregulated in astrocytes during normative aging and are linked to HA accumulation in gray matter.
Journal ArticleDOI
Hyaluronan Synthesis, Catabolism, and Signaling in Neurodegenerative Diseases
TL;DR: It is suggested that targeting HA synthesis, catabolism, and signaling are all potential strategies to promote CNS repair through mechanisms that include the regulation of progenitor cell differentiation and proliferation.
Journal ArticleDOI
CD44 transmembrane receptor and hyaluronan regulate adult hippocampal neural stem cell quiescence and differentiation
Weiping Su,Scott Foster,Rubing Xing,Kerstin Feistel,Kerstin Feistel,Reid H.J. Olsen,Summer F. Acevedo,Jacob Raber,Larry S. Sherman +8 more
TL;DR: It is found that HA and CD44 play important roles in regulating adult neurogenesis, and evidence that HA contributes to age-related reductions in neural stem cell (NSC) expansion and differentiation in the hippocampus is provided.
Journal ArticleDOI
Japanese macaque encephalomyelitis: a spontaneous multiple sclerosis-like disease in a nonhuman primate
Michael K. Axthelm,Dennis Bourdette,Gail Marracci,Weiping Su,Elizabeth T. Mullaney,Minsha Manoharan,Steven G. Kohama,Jim Pollaro,Ellen Witkowski,Paul Wang,William D. Rooney,Larry S. Sherman,Scott W. Wong +12 more
TL;DR: To describe Japanese macaque encephalomyelitis, a spontaneous inflammatory demyelinating disease occurring in the Oregon National Primate Research Center's (ONPRC) colony of Japanese macaques (JMs, Macaca fuscata).