Weishuang Zheng

Bio: Weishuang Zheng is an academic researcher from Peking University. The author has contributed to research in topics: Membrane. The author has an hindex of 1, co-authored 1 publications receiving 1 citations.

Multifunctional, Robust, and Porous PHBV-GO/MXene Composite Membranes with Good Hydrophilicity, Antibacterial Activity, and Platelet Adsorption Performance.

Abstract: The limitations of hydrophilicity, strength, antibacterial activity adsorption performance of the biobased and biocompatible polymer materials, such as polyhydroxyalkanoates (PHAs), significantly restrict their wider applications especially in medical areas. In this paper, a novel composite membrane with high antibacterial activity and platelet adsorption performance was prepared based on graphene oxide (GO), MXene and 3-hydroxybutyrate-co-hydroxyvalerate (PHBV), which are medium-chain-length-copolymers of PHA. The GO/MXene nanosheets can uniformly inset on the surface of PHBV fibre and give the PHBV—GO/MXene composite membranes superior hydrophilicity due to the presence of hydroxyl groups and terminal oxygen on the surface of nanosheets, which further provides the functional site for the free radical polymerization of ester bonds between GO/MXene and PHBV. As a result, the tensile strength, platelet adsorption, and blood coagulation time of the PHBV—GO/MXene composite membranes were remarkably increased compared with those of the pure PHBV membranes. The antibacterial rate of the PHBV—GO/MXene composite membranes against gram-positive and gram-negative bacteria can reach 97% due to the antibacterial nature of MXene. The improved strength, hydrophilicity, antibacterial activity and platelet adsorption performance suggest that PHBV—GO/MXene composite membranes might be ideal candidates for multifunctional materials for haemostatic applications.

MXenes Antibacterial Properties and Applications: A Review and Perspective.

Abstract: The mutations of bacteria due to the excessive use of antibiotics, and generation of antibiotic-resistant bacteria have made the development of new antibacterial compounds a necessity. MXenes have emerged as biocompatible transition metal carbide structures with extensive biomedical applications. This is related to the MXenes' unique combination of properties, including multifarious elemental compositions, 2D-layered structure, large surface area, abundant surface terminations, and excellent photothermal and photoelectronic properties. The focus of this review is the antibacterial application of MXenes, which has attracted the attention of researchers since 2016. A quick overview of the synthesis strategies of MXenes is provided and then summarizes the effect of various factors (including structural properties, optical properties, surface charges, flake size, and dispersibility) on the biocidal activity of MXenes. The main mechanisms for deactivating bacteria by MXenes are discussed in detail including rupturing of the bacterial membrane by sharp edges of MXenes nanoflakes, generating the reactive oxygen species (ROS), and photothermal deactivating of bacteria. Hybridization of MXenes with other organic and inorganic materials can result in materials with improved biocidal activities for different applications such as wound dressings and water purification. Finally, the challenges and perspectives of MXene nanomaterials as biocidal agents are presented.

Emerging advancements in MXene polysaccharide bionanoarchitectures and biomedical applications

Abstract: Polymeric bionanoarchitectures have demonstrated to be exceptional multifunctional materials and have attracted great interest as sustainable materials and panacea to multiple challenges. MXene (M-X) has emanated as a new set of 2-D materials capable of producing metallic conductivity when interacting with hydrophilic entities. M-X inherent delamination facilitates single-layer nanosheets of about one nm thickness and lateral size within the micrometric range. M-X delamination results in an elevated aspect ratio, making it a functional nanofiller for the multi-functionalization of polymeric bionanoarchitectures. Therefore, this elucidation is focused on M-X polysaccharide electroactively affiliated hydrogel bionanoarchitectures with special emphasis on M-X chitosan bionanoarchitectures, M-X cellulose bionanoarchitectures, M-X hyaluronic acid, and M-X alginate sodium bionanoarchitectures and their biomedical applications. Herein, the architectural disposition, properties, and multifaceted uses, in addition to challenges and future prospects of these materials, are presented.

MXene polymeric nanoarchitectures mechanical, deformation, and failure mechanism: A review

Abstract: ABSTRACT M-X have emanated as a potential material for numerous mechanical uses ascribed to their exceptional physicochemical features, multilayered architectures, superior strength, and electrical conductivity along with their flexibility. The mechanical features of M-X polymeric nanoarchitectures are critical to their application in advanced engineering structures and include Young’s modulus, bending rigidity, elasticity, sliding resistance, adhesion, ideal strengths, theoretical and experimental affiliations. Furthermore, the deformation along with failure mechanism of materials are essential in engineering applications. Engineering finite elemental models as well as prediction of M-X nanosheets mechanical behavior are imperative in understanding the mechanical behavior of M-X/polymeric nanoarchitectures. Therefore, this paper elucidates the mechanical, deformation, and failure mechanism of M-X and M-X polymeric nanoarchitectures with special emphasis on models utilized in predicting the mechanical behaviors of these materials. Graphical Abstract