Wenshan Wang

TL;DR: F Fate-mapping analyses have identified progenitor populations that give rise to brown and beige fat cells, and have revealed unanticipated cell-lineage relationships between vascular smooth muscle cells and bege adipocytes, and between skeletal Muscle cells and brown fat.

TL;DR: Results show that Prdm16 and Prdm3 control postnatal BAT identity and function and Interestingly, the loss of brown fat identity due to ablation of PrDM16 was accelerated by concurrent deletion of the closely related PrDM3 gene.

TL;DR: Results indicate that Ebf2 specifically marks and regulates the molecular profile of brown preadipose cells and reveals that EbF2 functions to control brown predipose cell identity.

TL;DR: It is demonstrated that adipocytes secrete a metabolite signal that controls beige fat remodeling and dietary BHB supplementation in aged animals reduced adipose fibrosis and promoted beigefat formation.

TL;DR: The in vivo functional expression of 12 selected receptors was examined by micro‐injecting agonists into live mouse BAT and analyzing the metabolic response, showing that the expression of classic BA markers is more complex and variable than previously thought.