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Werner M. Kistler
Researcher at Erasmus University Rotterdam
Publications - 21
Citations - 4747
Werner M. Kistler is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Cerebellar cortex & Cerebellum. The author has an hindex of 11, co-authored 21 publications receiving 4252 citations.
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Book
Spiking Neuron Models: Single Neurons, Populations, Plasticity
TL;DR: A comparison of single and two-dimensional neuron models for spiking neuron models and models of Synaptic Plasticity shows that the former are superior to the latter, while the latter are better suited to population models.
Book
Neuronal Dynamics: From Single Neurons to Networks and Models of Cognition
TL;DR: This textbook for advanced undergraduate and beginning graduate students provides a thorough and up-to-date introduction to the fields of computational and theoretical neuroscience.
Journal ArticleDOI
Mathematical formulations of Hebbian learning.
TL;DR: With an appropriate choice of parameters, Hebbian synaptic plasticity has intrinsic normalization properties that stabilizes postsynaptic firing rates and leads to subtractive weight normalization.
Journal ArticleDOI
Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice
Casper C. Hoogenraad,Bas K Koekkoek,Anna Akhmanova,Harm J. Krugers,Bjorn R. Dortland,Marja Miedema,Arjan M. van Alphen,Werner M. Kistler,Martine Jaegle,Manoussos Koutsourakis,Nadja Van Camp,Marleen Verhoye,Annemie Van der Linden,Irina Kaverina,Frank Grosveld,Chris I. De Zeeuw,Niels Galjart +16 more
TL;DR: Evidence is provided that mice with haploinsufficiency for Cyln2 have features reminiscent of Williams syndrome, including mild growth deficiency, brain abnormalities, hippocampal dysfunction and particular deficits in motor coordination, using a gene-targeting approach.
Journal ArticleDOI
Deformation of Network Connectivity in the Inferior Olive of Connexin 36-Deficient Mice Is Compensated by Morphological and Electrophysiological Changes at the Single Neuron Level
Chris I. De Zeeuw,Edilzh Chorev,Anna Devor,Yait Manor,Ruben S. Van Der Giessen,Marcel T. G. de Jeu,Casper C. Hoogenraad,J. Bijman,Tom J. H. Ruigrok,Pim J. French,Dick Jaarsma,Werner M. Kistler,Carola Meier,Elisabeth Petrasch-Parwez,Rolf Dermietzel,Goran Söhl,Martin Gueldenagel,Klaus Willecke,Yosi Yarom +18 more
TL;DR: It is concluded that the absence of Cx36 in the inferior olive is not compensated by the formation of other gap-junction channels but instead by changes in the cytological and electroresponsive properties of its neurons, such that the capability to produce rhythmic activity is maintained.