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Willem Welboren
Researcher at Radboud University Nijmegen
Publications - 3
Citations - 1861
Willem Welboren is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Chromatin & Gene. The author has an hindex of 3, co-authored 3 publications receiving 1688 citations.
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Journal ArticleDOI
An oestrogen-receptor-α-bound human chromatin interactome
Melissa J. Fullwood,Mei Hui Liu,You Fu Pan,Jun Liu,Han Xu,Yusoff Bin Mohamed,Yuriy L. Orlov,Stoyan Velkov,Andrea Ho,Poh Huay Mei,Elaine G.Y. Chew,Phillips Yao Hui Huang,Willem Welboren,Yuyuan Han,Hong Sain Ooi,Pramila N. Ariyaratne,Vinsensius B. Vega,Yanquan Luo,Peck Yean Tan,Pei Ye Choy,K. D. Senali Abayratna Wansa,Bing Zhao,Kar Sian Lim,Shi Chi Leow,Jit Sin Yow,Roy Joseph,Haixia Li,Kartiki V. Desai,Jane S. Thomsen,Yew Kok Lee,R. Krishna Murthy Karuturi,Thoreau Herve,Guillaume Bourque,Hendrik G. Stunnenberg,Xiaoan Ruan,Valere Cacheux-Rataboul,Wing-Kin Sung,Wing-Kin Sung,Edison T. Liu,Chia-Lin Wei,Edwin Cheung,Edwin Cheung,Edwin Cheung,Yijun Ruan,Yijun Ruan +44 more
TL;DR: It is proposed that chromatin interactions constitute a primary mechanism for regulating transcription in mammalian genomes and is described as a new strategy, chromatin interaction analysis by paired-end tag sequencing (ChIA-PET) for the de novo detection of global Chromatin interactions.
Journal ArticleDOI
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells.
Pantelis Hatzis,Laurens G. van der Flier,Marc A. van Driel,Victor Guryev,Fiona G. G. Nielsen,Sergei Denissov,Isaac J. Nijman,Jan Koster,Evan E. Santo,Willem Welboren,Rogier Versteeg,Edwin Cuppen,Marc van de Wetering,Hans Clevers,Hendrik G. Stunnenberg +14 more
TL;DR: Through a DNA array-based genome-wide analysis of TCF4 chromatin occupancy, 6,868 high-confidenceTCF4-binding sites are identified in the LS174T colorectal cancer cell line and significantly correlate with Wnt-responsive gene expression profiles derived from primary human adenomas.
Journal ArticleDOI
The ornithine cycle enzyme arginase from Agaricus bisporus and its role in urea accumulation in fruit bodies
Matthijs J. M. Wagemaker,Willem Welboren,Chris van der Drift,Mike S. M. Jetten,Leo J.L.D. Van Griensven,Huub J. M. Op den Camp +5 more
TL;DR: The arginase gene was used as a molecular marker to study expression and regulation during sporophore formation and postharvest development and a good correlation was found betweenArginase expression and urea content of stipe, velum, gills, cap and peel tissue.