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William Clark

Researcher at St George's Hospital

Publications -  27
Citations -  1448

William Clark is an academic researcher from St George's Hospital. The author has contributed to research in topics: Percutaneous vertebroplasty & Osteoporosis. The author has an hindex of 11, co-authored 22 publications receiving 1303 citations. Previous affiliations of William Clark include University of New South Wales.

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Journal ArticleDOI

Management of acute osteoporotic vertebral fractures: a nonrandomized trial comparing percutaneous vertebroplasty with conservative therapy

TL;DR: In this paper, percutaneous vertebroplasty was used to stabilize a fractured vertebral body, which resulted in a 53% reduction in pain scores (from 19 to 9; P 0.0001) and a 29% improvement in physical functioning.
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Safety and efficacy of vertebroplasty for acute painful osteoporotic fractures (VAPOUR): a multicentre, randomised, double-blind, placebo-controlled trial

TL;DR: Vertebroplasty is superior to placebo intervention for pain reduction in patients with acute osteoporotic spinal fractures of less than 6 weeks' in duration, and will allow Patients with acute painful fractures to have an additional means of pain management that is known to be effective.
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Clinical outcomes after acute osteoporotic vertebral fractures: a 2-year non-randomised trial comparing percutaneous vertebroplasty with conservative therapy.

TL;DR: Objective: To assess the safety and efficacy of percutaneous vertebroplasty for the treatment of acute osteoporotic vertebral fractures.
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Prospective study of alcoholism treatment: Eight-year follow-up

TL;DR: Premorbid social stability and Alcoholics Anonymous attendance made independent contributions to sustained abstinence and factors other than professionally organized treatment per se exert substantial effect upon long-term outcome.
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Percutaneous imaging-guided radiofrequency ablation in patients with colorectal pulmonary metastases: 1-year follow-up.

TL;DR: Percutaneous imaging–guided RFA of multiple colorectal pulmonary metastases is a minimally invasive treatment option with modest morbidity, and a significant proportion of patients show good evidence of successful local control at 1 year.