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William E. Russell
Researcher at Vanderbilt University
Publications - 84
Citations - 10781
William E. Russell is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Liver regeneration & Epidermal growth factor. The author has an hindex of 33, co-authored 79 publications receiving 10021 citations. Previous affiliations of William E. Russell include University of Illinois at Chicago & Ruhr University Bochum.
Papers
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Journal ArticleDOI
Osteoporosis prevention, diagnosis, and therapy
Anne Klibanski,Lucile L. Adams-Campbell,Tamsen Bassford,Steven N. Blair,Scott D. Boden,Kay Dickersin,David R. Gifford,Lou Glasse,Steven R. Goldring,Keith A. Hruska,Susan R. Johnson,Laurie K. McCauley,William E. Russell +12 more
TL;DR: Though prevalent in white postmenopausal women, osteoporosis occurs in all populations and at all ages and has significant physical, psychosocial, and financial consequences.
Journal ArticleDOI
An Essential Role for Ectodomain Shedding in Mammalian Development
Jacques J. Peschon,Jennifer L. Slack,Pranitha Reddy,Kim L. Stocking,Susan W. Sunnarborg,David C. Lee,William E. Russell,Beverly J. Castner,Richard S. Johnson,Jeffrey N. Fitzner,Rogely W. Boyce,Nicole Nelson,Carl J. Kozlosky,Martin F. Wolfson,Charles Rauch,Douglas P. Cerretti,Raymond J. Paxton,Carl J. March,Roy A. Black +18 more
TL;DR: The phenotype of mice lacking TACE suggests an essential role for soluble TGFalpha in normal development and emphasizes the importance of protein ectodomain shedding in vivo.
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Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability.
Susan W. Sunnarborg,C. Leann Hinkle,Mary C. Stevenson,William E. Russell,Christina S. Raska,Jacques J. Peschon,Beverly J. Castner,Mary Gerhart,Raymond J. Paxton,Roy A. Black,David C. Lee +10 more
TL;DR: A broad role for TACE in the regulated shedding of EGFR ligands is supported, showing that cells lacking TACE activity shed dramatically less TGF-α as compared with wild-type cultures and that T GF-α cleavage was partially restored by infection of Tace-deficient cells with TACE-encoding adenovirus.
Journal ArticleDOI
Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat
TL;DR: TGF- beta 1 and TGF-beta 2 reversibly inhibit the proliferative response of liver to PH and may be important in the modulation of normal liver growth and repair.
Journal ArticleDOI
Epidermal growth factor-related peptides and their relevance to gastrointestinal pathophysiology.
John A. Barnard,R. Daniel Beauchamp,William E. Russell,Raymond N. DuBois,Raymond N. DuBois,Robert J. Coffey,Robert J. Coffey +6 more
TL;DR: The biology and significance of the epidermal growth factor (EGF) family is reviewed, with particular emphasis on understanding the integrated function of the family and the relationships between family members in the context of gastrointestinal physiology and pathophysiology.