William F. Marzluff

TL;DR: High-throughput sequencing of libraries prepared from ribosome-depleted RNA with or without digestion with the RNA exonuclease showed that ecircRNAs are abundant, stable, conserved and nonrandom products of RNA splicing that could be involved in control of gene expression.

TL;DR: The sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus is reported, a model for developmental and systems biology and yields insights into the evolution of deuterostomes.

TL;DR: Results suggest that the coordinated synthesis of replication- dependent and variant histone mRNAs is achieved by signals that affect formation of the 3′ end of the replication-dependent histonemRNAs.

TL;DR: The multigene family encoding the five classes of replication-dependent histones has been identified from the human and mouse genome sequence, and the complexity of the histone protein complement significantly greater than previously thought.

TL;DR: RNAi experiments demonstrate that both the exosome and 5'-to-3' decay pathway components are required for degradation, and individual histone mRNAs are then degraded simultaneously 5' to 3' and 3' to 5'.