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Showing papers by "William G. Hunter published in 1966"


Journal ArticleDOI
TL;DR: A review of the literature of response surface methodology, emphasizing especially the practical applications of the method can be found in this article, where a comprehensive bibliography is also provided, with a focus on the application of the response surface strategy in chemistry and chemical engineering.
Abstract: Response surface methodology, an experimental strategy initially developed and described by Box and Wilson, has been employed with considerable success in a wide variety of situations, especially in the fields of chemistry and chemical engineering. It is the purpose of this paper to review the literature of response surface methodology, emphasizing especially the practical applications of the method. A comprehensive bibliography is included.

402 citations


Journal ArticleDOI
TL;DR: In this paper, a criterion for the choice of n experimental runs in multiresponse situations, after N runs are already available, is developed, applied to three examples involving two particular non-linear multiple response models and the results are discussed.
Abstract: : A criterion is developed for the choice of n experimental runs in multiresponse situations, after N runs are already available. The criterion is applied to three examples involving two particular non-linear multiple response models and the results are discussed.

145 citations


Journal ArticleDOI
TL;DR: Evolutionary operation, as originally presented by G. E. P. Box in 1957, is now an accepted means of improving the performance of industrial processes as mentioned in this paper, and numerous articles have been published relating to the successful application of this procedure.
Abstract: Evolutionary operation, as originally presented by G. E. P. Box in 1957, is now an accepted means of improving the performance of industrial processes. Numerous articles have since been published relating to the successful application of this procedure and they indicate that the technique is one of general industrial importance. It is the purpose of this article to review briefly these applications, thus providing a source of references useful both to those familiar with EVOP and those wishing to examine the potential applicability of the method for an existing process.

28 citations


Journal ArticleDOI
TL;DR: In this article, the authors present a method to select data points such that the confidence region of the estimated parameters is smaller with each data point than with any other possible data point within the region of experimentation.
Abstract: A method is reviewed which allows data points to be chosen in such a fashion that precise estimates of the parameters in nonlinear reaction rate models can be obtained. This method allows each future data point to be selected such that the confidence region of the estimated parameters is smaller with it than with any other possible data point within the region of experimentation. This procedure is applied for Hougen-Watson models with hypothetical experimental data which were generated with the guidance of an example from the current chemical engineering literature. It is found that, for the same number of data points, the parameters in the model can be estimated eighteen times more precisely by using this suggested experimental design than by another commonly used design. Confidence regions are presented for the parameters of the Hougen-Watson models with two types of designs. It is found that the positions of the data points in the well-designed experiments are more sensitive to the functional form of the model than to the current estimates of the magnitudes of the parameter values.

23 citations