William G. Hunter

Bio: William G. Hunter is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Model building & Design of experiments. The author has an hindex of 31, co-authored 61 publications receiving 15065 citations.

Discussion of: Statistical Comparison of Multiple Analytic Procedures: Application to Clinical Chemistry

Abstract: The paper by Lawton, Sylvestre, and Young addresses the important problem of the statistical comparison of several analytic methods (all for measuring the same thing) when no referee method is available. The authors propose a multivariate approach to the problem, which provides estimates of some of the components of variance for each method. The procedure is intended for situations in which fairly large data sets are available from more than two methods. We tried our hand at implementing the recommended procedure on the data set used in the paper by Carey, Wold, and Westgard [2], which was used for the illustrative example in the paper under discussion. We will call this the Carey data set. We also tried the procedure on a smaller set of constructed data. The calculations are easy to program, provided one already has programs to invert matrices and to compute eigenvalues and eigenvectors.

International Activities and the American Statistical Association

Abstract: This article describes the increasing involvement of the American Statistical Association (ASA) in international activities, and in particular, the events leading to the formation of the ASA Committee on International Relations in Statistics. ASA's emerging international program, which is currently being considered by this committee, is discussed.

Experimental Design and Data Analysis for Biologists

Abstract: An essential textbook for any student or researcher in biology needing to design experiments, sample programs or analyse the resulting data The text begins with a revision of estimation and hypothesis testing methods, covering both classical and Bayesian philosophies, before advancing to the analysis of linear and generalized linear models Topics covered include linear and logistic regression, simple and complex ANOVA models (for factorial, nested, block, split-plot and repeated measures and covariance designs), and log-linear models Multivariate techniques, including classification and ordination, are then introduced Special emphasis is placed on checking assumptions, exploratory data analysis and presentation of results The main analyses are illustrated with many examples from published papers and there is an extensive reference list to both the statistical and biological literature The book is supported by a website that provides all data sets, questions for each chapter and links to software

Quality Engineering Using Robust Design

Abstract: From the Publisher: Phadke was trained in robust design techniques by Genichi Taguchi, the mastermind behind Japanese quality manufacturing technologies and the father of Japanese quality control. Taguchi's approach is currently under consideration to be adopted as a student protocol with the US govrnment. The foreword is written by Taguchi. This book offers a complete blueprint for structuring projects to achieve rapid completion with high engineering productivity during the research and development phase to ensure that high quality products can be made quickly and at the lowest possible cost. Some topics covered are: orthogonol arrays, how to construct orthogonal arrays, computer-aided robutst design techniques, dynamic systems design methods, and more.

Advanced Oxidation Processes for Organic Contaminant Destruction Based on the Fenton Reaction and Related Chemistry

Abstract: Fenton chemistry encompasses reactions of hydrogen peroxide in the presence of iron to generate highly reactive species such as the hydroxyl radical and possibly others. In this review, the complex mechanisms of Fenton and Fenton-like reactions and the important factors influencing these reactions, from both a fundamental and practical perspective, in applications to water and soil treatment, are discussed. The review covers modified versions including the photoassisted Fenton reaction, use of chelated iron, electro-Fenton reactions, and Fenton reactions using heterogeneous catalysts. Sections are devoted to nonclassical pathways, by-products, kinetics and process modeling, experimental design methodology, soil and aquifer treatment, use of Fenton in combination with other advanced oxidation processes or biodegradation, economic comparison with other advanced oxidation processes, and case studies.

Robust Tests for the Equality of Variances

Abstract: Alternative formulations of Levene's test statistic for equality of variances are found to be robust under nonnormality. These statistics use more robust estimators of central location in place of the mean. They are compared with the unmodified Levene's statistic, a jackknife procedure, and a χ2 test suggested by Layard which are all found to be less robust under nonnormality.

Sensitivity Analysis in Practice: A Guide to Assessing Scientific Models

Abstract: PREFACE. 1. A WORKED EXAMPLE. 1.1 A simple model. 1.2 Modulus version of the simple model. 1.3 Six--factor version of the simple model. 1.4 The simple model 'by groups'. 1.5 The (less) simple correlated--input model. 1.6 Conclusions. 2. GLOBAL SENSITIVITY ANALYSIS FOR IMPORTANCE ASSESSMENT. 2.1 Examples at a glance. 2.2 What is sensitivity analysis? 2.3 Properties of an ideal sensitivity analysis method. 2.4 Defensible settings for sensitivity analysis. 2.5 Caveats. 3. TEST CASES. 3.1 The jumping man. Applying variance--based methods. 3.2 Handling the risk of a financial portfolio: the problem of hedging. Applying Monte Carlo filtering and variance--based methods. 3.3 A model of fish population dynamics. Applying the method of Morris. 3.4 The Level E model. Radionuclide migration in the geosphere. Applying variance--based methods and Monte Carlo filtering. 3.5 Two spheres. Applying variance based methods in estimation/calibration problems. 3.6 A chemical experiment. Applying variance based methods in estimation/calibration problems. 3.7 An analytical example. Applying the method of Morris. 4. THE SCREENING EXERCISE. 4.1 Introduction. 4.2 The method of Morris. 4.3 Implementing the method. 4.4 Putting the method to work: an analytical example. 4.5 Putting the method to work: sensitivity analysis of a fish population model. 4.6 Conclusions. 5. METHODS BASED ON DECOMPOSING THE VARIANCE OF THE OUTPUT. 5.1 The settings. 5.2 Factors Prioritisation Setting. 5.3 First--order effects and interactions. 5.4 Application of Si to Setting 'Factors Prioritisation'. 5.5 More on variance decompositions. 5.6 Factors Fixing (FF) Setting. 5.7 Variance Cutting (VC) Setting. 5.8 Properties of the variance based methods. 5.9 How to compute the sensitivity indices: the case of orthogonal input. 5.9.1 A digression on the Fourier Amplitude Sensitivity Test (FAST). 5.10 How to compute the sensitivity indices: the case of non--orthogonal input. 5.11 Putting the method to work: the Level E model. 5.11.1 Case of orthogonal input factors. 5.11.2 Case of correlated input factors. 5.12 Putting the method to work: the bungee jumping model. 5.13 Caveats. 6. SENSITIVITY ANALYSIS IN DIAGNOSTIC MODELLING: MONTE CARLO FILTERING AND REGIONALISED SENSITIVITY ANALYSIS, BAYESIAN UNCERTAINTY ESTIMATION AND GLOBAL SENSITIVITY ANALYSIS. 6.1 Model calibration and Factors Mapping Setting. 6.2 Monte Carlo filtering and regionalised sensitivity analysis. 6.2.1 Caveats. 6.3 Putting MC filtering and RSA to work: the problem of hedging a financial portfolio. 6.4 Putting MC filtering and RSA to work: the Level E test case. 6.5 Bayesian uncertainty estimation and global sensitivity analysis. 6.5.1 Bayesian uncertainty estimation. 6.5.2 The GLUE case. 6.5.3 Using global sensitivity analysis in the Bayesian uncertainty estimation. 6.5.4 Implementation of the method. 6.6 Putting Bayesian analysis and global SA to work: two spheres. 6.7 Putting Bayesian analysis and global SA to work: a chemical experiment. 6.7.1 Bayesian uncertainty analysis (GLUE case). 6.7.2 Global sensitivity analysis. 6.7.3 Correlation analysis. 6.7.4 Further analysis by varying temperature in the data set: fewer interactions in the model. 6.8 Caveats. 7. HOW TO USE SIMLAB. 7.1 Introduction. 7.2 How to obtain and install SIMLAB. 7.3 SIMLAB main panel. 7.4 Sample generation. 7.4.1 FAST. 7.4.2 Fixed sampling. 7.4.3 Latin hypercube sampling (LHS). 7.4.4 The method of Morris. 7.4.5 Quasi--Random LpTau. 7.4.6 Random. 7.4.7 Replicated Latin Hypercube (r--LHS). 7.4.8 The method of Sobol'. 7.4.9 How to induce dependencies in the input factors. 7.5 How to execute models. 7.6 Sensitivity analysis. 8. FAMOUS QUOTES: SENSITIVITY ANALYSIS IN THE SCIENTIFIC DISCOURSE. REFERENCES. INDEX.