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William J. Giardina
Publications - 2
Citations - 84
William J. Giardina is an academic researcher. The author has contributed to research in topics: Circadian rhythm & Imipramine. The author has an hindex of 2, co-authored 2 publications receiving 82 citations.
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Positive effects of captopril in the behavioral despair swim test.
TL;DR: The blockade of the captopril effects by naloxone suggests that brain opioid peptides play a role in this behavioral effect ofcaptopril, and the conclusion is guarded, as the positive effects may be related to motor stimulation.
Journal ArticleDOI
Effects of imipramine on the nocturnal behavior of bilateral olfactory bulbectomized rats.
William J. Giardina,R.J. Redek +1 more
TL;DR: Seven daily injections of imipramine significantly reduced the nocturnal activity of OB rats, such that OB rats displayed noct nighttime activity equivalent to SO rats, which may prove to be valuable for the evaluation of novel antidepressive compounds.