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Author

William J. Kluck

Bio: William J. Kluck is an academic researcher. The author has contributed to research in topics: Ullage & Fluid dynamics. The author has an hindex of 6, co-authored 6 publications receiving 491 citations.

Papers
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Patent
11 Oct 1996
TL;DR: In this paper, a conformable ullage made of yielding materials which uniquely conform to the shape of the elastomeric membrane was constructed for a low profile, laminate or layered construction.
Abstract: This invention is an apparatus (10) for accurately infusing fluids into a patient at specific rates over an extended period of time. The apparatus (10) is of a low profile, laminate or layered construction having a stored energy source in the form of a distended membrane (28), which in cooperation with the base (12) of the apparatus (10), defines one or more fluid reservoirs (20), each having a fluid inlet (22) and a fluid outlet (32). The apparatus further includes a novel conformable ullage made of yielding materials which uniquely conform to the shape of the elastomeric membrane (28) as the membrane (28) returns to its less distended configuration. This arrangement will satisfy even the most stringent medicament delivery tolerance requirements, and will elegantly overcome the limitations of materials selection encountered in devices embodying solely a rigid ullage construction. Additionally, in one form of the invention, the apparatus includes a novel fill assembly (302) for controllably filling the reservoirs of the device in the field.

188 citations

Patent
26 May 1995
TL;DR: In this article, an apparatus for accurately infusing medicinal agents into an ambulatory patient at specific rates over extended periods of time is described. The apparatus is of a compact, low profile laminate construction and includes an elastic distendable membrane (34), which, in cooperation with a thin planar base, defines a fluid chamber having a fluid outlet.
Abstract: An apparatus (30) for accurately infusing medicinal agents into an ambulatory patient at specific rates over extended periods of time. The apparatus (30) is of a compact, low profile laminate construction and includes an elastic distendable membrane (34), which, in cooperation with a thin planar base (32) defines a fluid chamber (46) having a fluid outlet. Disposed within the fluid chamber (46) is a thin fluid permeable member (66) which precisely controls the rate of fluid flow through the fluid outlet. The apparatus (30) also includes a highly novel fluid flow indicator (104) that provides a readily discernible visual indication of fluid flow through the apparatus (30).

82 citations

Patent
11 Oct 1995
TL;DR: In this article, a low profile, laminate or layered construction with a stored energy source in the form of a distendable membrane, which, in cooperation with the base of the apparatus, defines one or more fluid reservoirs, each having a fluid inlet and a fluid outlet.
Abstract: An apparatus for accurately infusing fluids into a patient at specific rates over an extended period of time. The apparatus is of a low profile, laminate or layered construction having a stored energy source in the form of a distendable membrane, which, in cooperation with the base of the apparatus, defines one or more fluid reservoirs, each having a fluid inlet and a fluid outlet. The apparatus further includes, a high novel, conformable ullage made of yieldable materials. The conformable ullage uniquely conforms to the shape of elastomeric membrane as the membrane returns to its less distended configuration. Additionally, the infusion cannula of the apparatus is connected to the base in a novel manner which permits expeditious subdermal delivery to the patient via a cannula which extends generally perpendicularly relative to the base. The cannula is connected to the base in a manner such that the pierceable portion of the cannula is free to move relative to the base of the device in response to movements by the patient which cause flexing of the muscle and tissue in the vicinity of the cannula.

76 citations

Patent
11 Oct 1995
TL;DR: In this article, a conformable ullage made of yieldable materials is proposed for a low profile, laminate or layered construction having a stored energy source in the form of a distendable membrane, which defines one or more fluid reservoirs, each having a fluid inlet and a fluid outlet.
Abstract: An apparatus for accurately infusing fluids into a patient at specific rates over an extended period of time. The apparatus is of a low profile, laminate or layered construction having a stored energy source in the form of a distendable membrane, which, in cooperation with the base of the apparatus, defines one or more fluid reservoirs, each having a fluid inlet and a fluid outlet. The apparatus further includes, a novel conformable ullage made of yieldable materials. The conformable ullage uniquely conforms to the geometry of elastomeric membrane as the membrane returns to its less distended configuration and in so doing can move between a central chamber and a toroidal chamber formed in the cover of the apparatus. This arrangement will satisfy even the most stringent medicament delivery tolerance requirements and will elegantly overcome the limitations of materials selection encountered in devices embodying solely a rigid ullage construction. Additionally, the infusion cannula of the apparatus is connected to the base in a novel manner which permits expeditious subdermal delivery to the patient via a cannula which extends generally perpendicularly relative to the base.

58 citations

Patent
16 Dec 1997
TL;DR: In this paper, a fluid delivery device for infusing medicinal fluids having a self-contained stored energy membrane for expelling fluids at a precisely controlled rate is presented, which can conveniently be used for the fluids, such as insulin and the like, into an ambulatory patient at controlled rates over extended periods of time.
Abstract: A fluid delivery device for infusing medicinal fluids having a self-contained stored energy membrane for expelling fluids at a precisely controlled rate. The device is of a compact, low profile, laminate construction so that it can conveniently be used for the fluids, such as insulin and the like, into an ambulatory patient at controlled rates over extended periods of time. Included within the device are various fluid flow control elements including a unique hydraulic fluid rate control system for ultra low flow delivery. Also included is a highly novel flow indictor for providing a positive indication of fluid flow from the device and for indicating at any given time the amount of fluid remaining in the device.

46 citations


Cited by
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Patent
31 Aug 2001
TL;DR: In this article, the authors describe a system for delivering a fluid to a patient, including an exit port, a dispenser for causing fluid from a reservoir to flow to the exit port and a local processor programmed to cause a flow of fluid to the exiting port based on flow instructions from a separate, remote control device.
Abstract: A device for delivering a fluid to a patient, including an exit port, a dispenser for causing fluid from a reservoir to flow to the exit port, a local processor programmed to cause a flow of fluid to the exit port based on flow instructions from a separate, remote control device, and a wireless receiver connected to the local processor for receiving the flow instructions. The device also includes a housing free of user input components for providing flow instructions to the local processor, in order to reduce the complexity and costs of the device so that the device lends itself to being disposable in nature. A system and a kit are also described that include the fluid delivery device, a separate, remote control device, and accessories for transcutaneous delivery of fluid medications. Methods of utilizing the fluid delivery device to infuse fluid medications are additionally disclosed.

755 citations

Patent
22 Feb 2002
TL;DR: In this paper, a device for delivering fluid including a disposable assembly (800) having an exit port assembly (70) and a metering portion of a dispenser (40) for controlling fluid flow to the exit port assemblies (70), and a reusable assembly (700) having a control portion (46) of the dispenser(40) adapted to control the metering component of the dispenser (40), upon attachment of the reusable assembly(700) and the disposable assembly(800), a local processor (50) connected to the dispensers (40).
Abstract: A device (10) for delivering fluid including a disposable assembly (800) having an exit port assembly (70) and a metering portion of a dispenser (40) for controlling fluid flow to the exit port assembly (70), and a reusable assembly (700) having a control portion (46) of the dispenser (40) adapted to control the metering portion of the dispenser (40) upon attachment of the reusable assembly (700) and the disposable assembly (800), a local processor (50) connected to the dispenser (40) and programmed to cause fluid flow to the exit port assembly (70) through the dispenser (40) based upon flow instructions, and a local wireless communication element (60) connected to the local processor (50) for receiving flow instructions from a remote wireless device (100) The assemblies (700, 800) are adapted to be removably attached, and a power source (80) is contained in the disposable assembly (800) for providing power to the reusable assembly (700) upon attachment of the reusable assembly (700) and the disposable assembly (800)

676 citations

Patent
21 Dec 2001
TL;DR: In this paper, a system for providing medical treatment to a patient, including a medical treatment apparatus and a remote control device, is described, where information can be transferred between the local processor and the remote processor in a wireless manner.
Abstract: A system for providing medical treatment to a patient, including a medical treatment apparatus and a remote control device. The medical treatment apparatus has a local processor, and a local communication element connected to the local processor, while the remote control device includes a remote processor, user interface components connected to the remote processor, and a remote communication element connected to the remote processor and adapted to communicate with the local communication element of the medical treatment apparatus in a wireless manner such that information can be transferred between the local processor and the remote processor. The remote control device also includes at least two separate power supplies connected to the remote processor.

460 citations

Patent
09 Nov 2001
TL;DR: In this article, the authors describe a device for delivering fluid to a patient including a passageway having a proximal fluid transport tube, a distal fluid transport tubes, and a tubular expansion member coupling the fluid transport wires.
Abstract: A device (10) for delivering fluid to a patient including a passageway having a proximal fluid transport tube, a distal fluid transport tube, and a tubular expansion member coupling the fluid transport tubes. A penetrating member (704) is positioned within the expansion member for axial movement between the fluid transport tubes, and has a sharpened distal tip. The device also includes a dispenser (40) for causing fluid from a reservoir (30) to flow to the proximal fluid transport tube, a housing (20) containing the dispenser and the passageway and including an exit port (70) receiving the distal fluid transport tube, and a connecting member secured to the penetrating member. The connecting member is movable by a user from an exterior of the housing and arranged such that movement causes the penetrating member to move between an extended position and a retracted position.

454 citations

Patent
30 Aug 1996
TL;DR: In this paper, a cylindrical injection chamber was used to drive a medicament delivery device with a delivery needle mounted on the periphery of the lower surface of the housing, thereby providing a more stable temperature and more predictable operation of the device.
Abstract: A medicament delivery device (10) has a reservoir within a housing (11) and means for driving medicament from the reservoir. The device is provided with a filling mechanism upon which a medicament container (19) sealed by a penetrable stopper (25) is mounted. The mechanism comprises an internal bore (20) which accommodates an internal rod (21) from which a needle (22) projects. Needle (22) is hollow and is in communication with the reservoir. In order to fill the reservoir, the container (19) is pressed into the bore (20), causing the needle (22) to pierce the stopper (25), the stopper abutting against the rod (21) and acting as a piston to drive medicament from the container (19) as the container (19) is pushed into the bore (20) and moves relative to the stopper (25). Thus, the reservoir can be filled with the sterile medicament which is stable when stored in the container (19), and the filling is easily accomplished without the use of a syringe. A further advantageous feature is provided by a delivery needle which is mounted on the periphery of the lower surface of the housing. This configuration allows the driving means to be located adjacent to the skin, thereby, providing a more stable temperature and more predictable operation of the device.

437 citations