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William Lanier
Researcher at University of Iowa
Publications - 5
Citations - 2260
William Lanier is an academic researcher from University of Iowa. The author has contributed to research in topics: Gene silencing & Gene. The author has an hindex of 5, co-authored 5 publications receiving 2114 citations.
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Journal ArticleDOI
RNA polymerase III transcribes human microRNAs
TL;DR: The genomic analysis of miRNAs in the human chromosome 19 miRNA cluster (C19MC) revealed that they are interspersed among Alu repeats, and these findings extend the current view of miRNA origins and the transcriptional machinery driving their expression.
Journal ArticleDOI
Green Evolution and Dynamic Adaptations Revealed by Genomes of the Marine Picoeukaryotes Micromonas
Alexandra Z. Worden,Jae-Hyeok Lee,Thomas Mock,Pierre Rouzé,Melinda P. Simmons,Andrea Aerts,Andrew E. Allen,Marie L. Cuvelier,Marie L. Cuvelier,Evelyne Derelle,Meredith V. Everett,Elodie Foulon,Jane Grimwood,Jane Grimwood,Heidrun Gundlach,Bernard Henrissat,Carolyn A. Napoli,Sarah M. McDonald,Micaela S. Parker,Stephane Rombauts,Aasf Salamov,Peter von Dassow,Jonathan H. Badger,Pedro M. Coutinho,Elif Demir,Inna Dubchak,Chelle L. Gentemann,Wenche Eikrem,Jill E. Gready,Uwe John,William Lanier,Erika Lindquist,Susan Lucas,Klaus F. X. Mayer,Hervé Moreau,Fabrice Not,Robert Otillar,Olivier Panaud,Jasmyn Pangilinan,Ian T. Paulsen,Benoît Piégu,Aaron Poliakov,Steven Robbens,Jeremy Schmutz,Jeremy Schmutz,Eve Toulza,Tania Wyss,Alex N. Zelensky,Kemin Zhou,E. Virginia Armbrust,Debashish Bhattacharya,Ursula Goodenough,Yves Van de Peer,Igor V. Grigoriev +53 more
TL;DR: It is found that genomes from two isolates shared only 90% of their predicted genes, and divergence appears to have been facilitated by selection and acquisition processes that actively shape the repertoire of genes that are mutually exclusive between the two isolate differently than the core genes.
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Adenosine deamination in human transcripts generates novel microRNA binding sites
Glen M. Borchert,Brian L. Gilmore,Ryan M. Spengler,Yi Xing,William Lanier,Debashish Bhattacharya,Beverly L. Davidson +6 more
TL;DR: The results suggest the creation of miRNA regulatory sites as a novel function for ADAR activity, as well as significant correlations between A-to-I editing and changes in miRNA complementarities.
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Marsupial-specific microRNAs evolved from marsupial-specific transposable elements.
TL;DR: Findings reinforce the view that transposable elements are a previously unappreciated source of new, lineage-specific microRNAs in marsupial species Monodelphis domestica.
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EST analysis of Ostreococcus lucimarinus, the most compact eukaryotic genome, shows an excess of introns in highly expressed genes.
TL;DR: Results imply the existence of selective/functional roles for introns that are principally detectable in highly expressed genes in a species with a genome that has been recently subjected to a great reduction of non-coding DNA.