William T. Christianson

TL;DR: This is the first isolate of SIRS virus in the United States that fulfills Koch's postulates in producing the respiratory form of the disease in gnotobiotic piglets and the first report of isolation and propagation of the virus on a continuous cell line (CL2621).

TL;DR: The characterization of an isolate of swine infertility and respiratory syndrome (SIRS) virus (ATCC VR-2332) is reported and it is indicated that this isolate is a fastidious, nonhemagglutinating, enveloped RNA virus.

TL;DR: This study reports the antigenic relatedness of isolates of Lelystad virus collected in the Netherlands, Germany, and the United States, and found 4 European isolates resembled each other closely, but differed from the American isolates, and 3 American isolate differed antigenically from each other.

TL;DR: On the basis of the findings, virus isolate ATCC VR-2332 causes the reproductive failure associated with SIRS.

TL;DR: Two experiments were undertaken to evaluate whether porcine reproductive and respiratory syndrome (PRRS) virus was able to cross the placenta and infect midgestation Fetuses following intranasal inoculation of sows and whether PRRS virus directly infected fetuses following in utero inoculation.