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Wing-Kin Sung
Researcher at National University of Singapore
Publications - 335
Citations - 28128
Wing-Kin Sung is an academic researcher from National University of Singapore. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 64, co-authored 327 publications receiving 26116 citations. Previous affiliations of Wing-Kin Sung include University of Hong Kong & Yale University.
Papers
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Journal ArticleDOI
Comprehensive evaluation of common genetic variation within LRRK2 reveals evidence for association with sporadic Parkinson's disease
Lisa Skipper,Yi Li,Carine Bonnard,R. Pavanni,Yuen Yih,E. Chua,Wing-Kin Sung,Louis C.S. Tan,Meng-Cheong Wong,Eng-King Tan,Jianjun Liu +10 more
TL;DR: The first evidence that common genetic variation within LRRK2 contributes to the risk of sporadic PD in the Chinese population is provided, using a haplotype that dramatically increases disease risk when present in two copies.
Journal ArticleDOI
Protein subcellular localization prediction for Gram-negative bacteria using amino acid subalphabets and a combination of multiple support vector machines.
TL;DR: Clustering 20 amino acids into a few groups by the proposed greedy algorithm provides a new way to extract features from protein sequences to cover more adjacent amino acids and hence reduce the dimensionality of the input vector of protein features.
Journal ArticleDOI
Oseltamivir Ring Prophylaxis for Containment of 2009 H1N1 Influenza Outbreaks
Vernon J. Lee,Jonathan Yap,Alex R. Cook,Mark I-Cheng Chen,Joshua K. Tay,Boon Huan Tan,Jin Phang Loh,Seok Wei Chew,Wee Hong Victor Koh,Raymond T. P. Lin,Lin Cui,Charlie W.H. Lee,Wing-Kin Sung,Christopher W. Wong,Martin L. Hibberd,Wee Lee Kang,Benjamin Seet,Paul A. Tambyah +17 more
TL;DR: Oseltamivir ring chemoprophylaxis, together with prompt identification and isolation of infected personnel, was effective in reducing the impact of outbreaks of 2009 H1N1 influenza in semiclosed settings.
Journal ArticleDOI
Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates
Bernice Meng Qi Sim,Narisara Chantratita,Wen Fong Ooi,Tannistha Nandi,Ryan Tewhey,Vanaporn Wuthiekanun,Janjira Thaipadungpanit,Sarinna Tumapa,Pramila N. Ariyaratne,Wing-Kin Sung,Wing-Kin Sung,Xiao Hui Sem,Hui Hoon Chua,Kalpana Ramnarayanan,Chi Ho Lin,Yichun Liu,Edward J. Feil,Mindy B. Glass,Gladys Tan,Sharon J. Peacock,Sharon J. Peacock,Patrick Tan,Patrick Tan +22 more
TL;DR: The discovery of such novel variant strains demonstrates how unbiased genomic surveys of non-pathogenic isolates can reveal insights into the development and emergence of new pathogenic species.
Book ChapterDOI
A Space and Time Efficient Algorithm for Constructing Compressed Suffix Arrays
TL;DR: This paper initiates the study of constructing compressed suffix arrays directly from text with the main contribution is a new construction algorithm that uses only O(n) bits of working memory, and more importantly, the time complexity remains the same as before.