W
Witte J.G. Hoogendijk
Researcher at Erasmus University Rotterdam
Publications - 140
Citations - 15150
Witte J.G. Hoogendijk is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Major depressive disorder & Depression (differential diagnoses). The author has an hindex of 47, co-authored 121 publications receiving 13485 citations. Previous affiliations of Witte J.G. Hoogendijk include VU University Amsterdam & Erasmus University Medical Center.
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Journal ArticleDOI
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
Jordan W. Smoller,Kenneth S. Kendler,Nicholas John Craddock,Phil Lee,Benjamin M. Neale,John I. Nurnberger,Stephan Ripke,Susan L. Santangelo,Patrick F. Sullivan,Shaun Purcell,Richard Anney,Jan K. Buitelaar,Ayman H. Fanous,Stephen V. Faraone,Witte J.G. Hoogendijk,Klaus-Peter Lesch,Douglas F. Levinson,Roy H. Perlis,Marcella Rietschel,Brien P. Riley,Edmund J.S. Sonuga-Barke,Russell Schachar,Thomas G. Schulze,Anita Thapar,Michael C. Neale,Patrick Bender,Sven Cichon,Mark J. Daly,John R. Kelsoe,Thomas Lehner,Michael Conlon O'Donovan,Pablo V. Gejman,Jonathan Sebat,Pamela Sklar +33 more
TL;DR: The findings show that specific SNPs are associated with a range of psychiatric disorders of childhood onset or adult onset, and variation in calcium-channel activity genes seems to have pleiotropic effects on psychopathology.
Journal ArticleDOI
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
S. Hong Lee,Stephan Ripke,Stephan Ripke,Benjamin M. Neale,Benjamin M. Neale,Stephen V. Faraone,Shaun Purcell,Shaun Purcell,Shaun Purcell,Roy H. Perlis,Roy H. Perlis,Bryan J. Mowry,Bryan J. Mowry,Anita Thapar,Michael E. Goddard,John S. Witte,Devin Absher,Ingrid Agartz,Huda Akil,Farooq Amin,Ole A. Andreassen,Adebayo Anjorin,Richard Anney,Verneri Anttila,Dan E. Arking,Philip Asherson,Maria Helena Pinto de Azevedo,Lena Backlund,Judith A. Badner,Anthony J. Bailey,Tobias Banaschewski,Jack D. Barchas,Michael R. Barnes,Thomas B. Barrett,Nicholas Bass,Agatino Battaglia,Michael Bauer,Mònica Bayés,Frank Bellivier,Sarah E. Bergen,Sarah E. Bergen,Sarah E. Bergen,Wade H. Berrettini,Catalina Betancur,Catalina Betancur,Catalina Betancur,Thomas Bettecken,Joseph Biederman,Elisabeth B. Binder,Donald W. Black,Douglas Blackwood,Cinnamon S. Bloss,Michael Boehnke,Dorret I. Boomsma,Gerome Breen,Gerome Breen,René Breuer,Richard Bruggeman,Paul Cormican,Nancy G. Buccola,Jan K. Buitelaar,William E. Bunney,Joseph D. Buxbaum,William Byerley,Enda M. Byrne,Sian Caesar,Wiepke Cahn,Rita M. Cantor,Miguel Casas,Aravinda Chakravarti,Kimberly Chambert,Khalid Choudhury,Sven Cichon,Sven Cichon,C. Robert Cloninger,David A. Collier,Edwin H. Cook,Hilary Coon,Bru Cormand,Aiden Corvin,William Coryell,David Craig,Ian W. Craig,Jennifer Crosbie,Michael L. Cuccaro,David Curtis,Darina Czamara,Susmita Datta,Geraldine Dawson,Richard O. Day,Eco J. C. de Geus,Franziska Degenhardt,Srdjan Djurovic,Gary Donohoe,Alysa E. Doyle,Jubao Duan,Frank Dudbridge,Eftichia Duketis,Richard P. Ebstein,Howard J. Edenberg,Josephine Elia,Sean Ennis,Bruno Etain,Ayman H. Fanous,Ayman H. Fanous,Anne Farmer,I. Nicol Ferrier,Matthew Flickinger,Eric Fombonne,Tatiana Foroud,Josef Frank,Barbara Franke,Christine Fraser,Robert Freedman,Nelson B. Freimer,Christine M. Freitag,Marion Friedl,Louise Frisén,Louise Gallagher,Pablo V. Gejman,Lyudmila Georgieva,Elliot S. Gershon,Daniel H. Geschwind,Ina Giegling,Michael Gill,Scott D. Gordon,Katherine Gordon-Smith,Katherine Gordon-Smith,Elaine K. Green,Tiffany A. Greenwood,Dorothy E. Grice,Magdalena Gross,Detelina Grozeva,Weihua Guan,Weihua Guan,Hugh Gurling,Lieuwe de Haan,Jonathan L. Haines,Hakon Hakonarson,Joachim Hallmayer,Steven P. Hamilton,Marian L. Hamshere,Thomas Hansen,Annette M. Hartmann,Martin Hautzinger,Andrew C. Heath,Anjali K. Henders,Stefan Herms,Stefan Herms,Ian B. Hickie,Maria Hipolito,Susanne Hoefels,Peter Holmans,Florian Holsboer,Witte J.G. Hoogendijk,Jouke-Jan Hottenga,Christina M. Hultman,Vanessa Hus,Andres Ingason,Marcus Ising,Stéphane Jamain,Edward G. Jones,Ian Jones,Lisa Jones,Jung-Ying Tzeng,Anna K. Kähler,René S. Kahn,Radhika Kandaswamy,Matthew C. Keller,James L. Kennedy,Elaine Kenny,Lindsey Kent,Yunjung Kim,George Kirov,Sabine M. Klauck,Lambertus Klei,James A. Knowles,Martin A. Kohli,Daniel L. Koller,Bettina Konte,Ania Korszun,Lydia Krabbendam,Robert Krasucki,Jonna Kuntsi,Phoenix Kwan,Mikael Landén,Mikael Landén,Niklas Långström,Mark Lathrop,Jacob Lawrence,William Lawson,Marion Leboyer,David H. Ledbetter,Phil Lee,Todd Lencz,Todd Lencz,Klaus-Peter Lesch,Klaus-Peter Lesch,Douglas F. Levinson,Cathryn M. Lewis,Jun Li,Paul Lichtenstein,Jeffrey A. Lieberman,Danyu Lin,Don H. Linszen,Chunyu Liu,Falk W. Lohoff,Sandra K. Loo,Catherine Lord,Jennifer K. Lowe,Susanne Lucae,Donald J. MacIntyre,Pamela A. F. Madden,Elena Maestrini,Patrik K. E. Magnusson,Pamela B. Mahon,Wolfgang Maier,Anil K. Malhotra,Anil K. Malhotra,Shrikant Mane,Christa Lese Martin,Nicholas G. Martin,Manuel Mattheisen,Manuel Mattheisen,Keith Matthews,Morten Mattingsdal,Steven A. McCarroll,Kevin A. McGhee,James J. McGough,Patrick J. McGrath,Peter McGuffin,Melvin G. McInnis,Andrew M. McIntosh,Rebecca McKinney,Alan W. McLean,Francis J. McMahon,William M. McMahon,Andrew McQuillin,Helena Medeiros,Sarah E. Medland,Sandra Meier,Ingrid Melle,Fan Meng,Jobst Meyer,Christel M. Middeldorp,Lefkos T. Middleton,Vihra Milanova,Ana Miranda,Anthony P. Monaco,Anthony P. Monaco,Grant W. Montgomery,Jennifer L. Moran,Daniel Moreno-De-Luca,Gunnar Morken,Derek W. Morris,Eric M. Morrow,Valentina Moskvina,Pierandrea Muglia,Thomas W. Mühleisen,Walter J. Muir,Bertram Müller-Myhsok,Michael T. Murtha,Richard M. Myers,Inez Myin-Germeys,Michael C. Neale,Stan F. Nelson,Caroline M. Nievergelt,Ivan Nikolov,Vishwajit L. Nimgaonkar,Willem A. Nolen,Markus M. Nöthen,John I. Nurnberger,Evaristus A. Nwulia,Dale R. Nyholt,Colm O'Dushlaine,Robert D. Oades,Ann Olincy,Guiomar Oliveira,Line Olsen,Roel A. Ophoff,Roel A. Ophoff,Urban Ösby,Michael John Owen,Aarno Palotie,Jeremy R. Parr,Andrew D. Paterson,Carlos N. Pato,Michele T. Pato,Brenda W.J.H. Penninx,Michele L. Pergadia,Margaret A. Pericak-Vance,Benjamin S. Pickard,Jonathan Pimm,Joseph Piven,Danielle Posthuma,Danielle Posthuma,James B. Potash,Fritz Poustka,Peter Propping,Vinay Puri,Digby Quested,Emma M. Quinn,Josep Antoni Ramos-Quiroga,Henrik B. Rasmussen,Soumya Raychaudhuri,Soumya Raychaudhuri,Karola Rehnström,Andreas Reif,Marta Ribasés,John P. Rice,Marcella Rietschel,Kathryn Roeder,Herbert Roeyers,Lizzy Rossin,Aribert Rothenberger,Guy A. Rouleau,Douglas M. Ruderfer,Dan Rujescu,Alan R. Sanders,Stephen Sanders,Susan L. Santangelo,Susan L. Santangelo,Joseph A. Sergeant,Russell Schachar,Martin Schalling,Alan F. Schatzberg,William A. Scheftner,Gerard D. Schellenberg,Stephen W. Scherer,Nicholas J. Schork,Thomas G. Schulze,Thomas G. Schulze,Johannes Schumacher,Markus J. Schwarz,Edward M. Scolnick,Laura J. Scott,Jianxin Shi,Paul D. Shilling,Stanley I. Shyn,Jeremy M. Silverman,Susan L. Slager,Susan L. Smalley,Johannes H. Smit,Erin N. Smith,Edmund J.S. Sonuga-Barke,Edmund J.S. Sonuga-Barke,David St Clair,Matthew W. State,Michael Steffens,Hans-Christoph Steinhausen,Hans-Christoph Steinhausen,Hans-Christoph Steinhausen,John Strauss,Jana Strohmaier,T. Scott Stroup,James S. Sutcliffe,Peter Szatmari,Szabocls Szelinger,Srinivasa Thirumalai,Robert C. Thompson,Alexandre A. Todorov,Federica Tozzi,Jens Treutlein,Manfred Uhr,Edwin J. C. G. van den Oord,Gerard van Grootheest,Jim van Os,Astrid M. Vicente,Astrid M. Vicente,Astrid M. Vicente,Veronica J. Vieland,John B. Vincent,Peter M. Visscher,Christopher A. Walsh,Thomas H. Wassink,Stanley J. Watson,Myrna M. Weissman,Thomas Werge,Thomas F. Wienker,Ellen M. Wijsman,Gonneke Willemsen,Nigel Williams,A. Jeremy Willsey,Stephanie H. Witt,Wei Xu,Allan H. Young,Allan H. Young,Timothy W. Yu,Stanley Zammit,Peter P. Zandi,Peng Zhang,Frans G. Zitman,Sebastian Zöllner,Bernie Devlin,John R. Kelsoe,John R. Kelsoe,Pamela Sklar,Mark J. Daly,Mark J. Daly,Michael Conlon O'Donovan,Nicholas John Craddock,Patrick F. Sullivan,Jordan W. Smoller,Jordan W. Smoller,Kenneth S. Kendler,Naomi R. Wray +405 more
TL;DR: Empirical evidence of shared genetic etiology for psychiatric disorders can inform nosology and encourages the investigation of common pathophysiologies for related disorders.
Journal ArticleDOI
A mega-analysis of genome-wide association studies for major depressive disorder
Stephan Ripke,Naomi R. Wray,Cathryn M. Lewis,Steven P. Hamilton,Myrna M. Weissman,Gerome Breen,Enda M. Byrne,Douglas Blackwood,Dorret I. Boomsma,Sven Cichon,Andrew C. Heath,Florian Holsboer,Susanne Lucae,Pamela A. F. Madden,Nicholas G. Martin,Peter McGuffin,Pierandrea Muglia,Markus M. Noethen,Brenda P Penninx,Michele L. Pergadia,James B. Potash,Marcella Rietschel,Danyu Lin,Bertram Müller-Myhsok,Jianxin Shi,Stacy Steinberg,Hans J. Grabe,Paul Lichtenstein,Patrik K. E. Magnusson,Roy H. Perlis,Martin Preisig,Jordan W. Smoller,Kari Stefansson,Rudolf Uher,Zoltán Kutalik,Katherine E. Tansey,Alexander Teumer,Alexander Viktorin,Michael R. Barnes,Thomas Bettecken,Elisabeth B. Binder,René Breuer,Victor M. Castro,Susanne Churchill,William Coryell,Nicholas John Craddock,Ian W. Craig,Darina Czamara,Eco J. C. de Geus,Franziska Degenhardt,Anne Farmer,Maurizio Fava,Josef Frank,Vivian S. Gainer,Patience J. Gallagher,Scott D. Gordon,Sergey Goryachev,Magdalena Gross,Michel Guipponi,Anjali K. Henders,Stefan Herms,Ian B. Hickie,Susanne Hoefels,Witte J.G. Hoogendijk,Jouke-Jan Hottenga,Dan V. Iosifescu,Marcus Ising,Ian Jones,Lisa Jones,Tzeng Jung-Ying,James A. Knowles,Isaac S. Kohane,Martin A. Kohli,Ania Korszun,Mikael Landén,William Lawson,Glyn Lewis,Donald J. MacIntyre,Wolfgang Maier,Manuel Mattheisen,Patrick J. McGrath,Andrew M. McIntosh,Alan W. McLean,Christel M. Middeldorp,Lefkos T. Middleton,G. M. Montgomery,Shawn N. Murphy,Matthias Nauck,Willem A. Nolen,Dale R. Nyholt,Michael Conlon O'Donovan,Hogni Oskarsson,Nancy L. Pedersen,William A. Scheftner,Andrea Schulz,Thomas G Schulze,Stanley I. Shyn,Engilbert Sigurdsson,Susan L. Slager,Johannes H. Smit,Hreinn Stefansson,Michael Steffens,Thorgeir E. Thorgeirsson,Federica Tozzi,Jens Treutlein,Manfred Uhr,Edwin J. C. G. van den Oord,Gerard van Grootheest,Henry Völzke,Jeffrey B. Weilburg,Gonneke Willemsen,Frans G. Zitman,Benjamin M. Neale,Mark J. Daly,Douglas F. Levinson,Patrick F. Sullivan +115 more
TL;DR: This article conducted a genome-wide association studies (GWAS) mega-analysis for major depressive disorder (MDD) using more than 1.2 million autosomal and X chromosome single-nucleotide polymorphisms (SNPs) in 18,759 independent and unrelated subjects of recent European ancestry.
Journal ArticleDOI
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
Rixt F. Riemersma-van der Lek,Dick F. Swaab,Jos W. R. Twisk,Elly M. Hol,Witte J.G. Hoogendijk,Eus J.W. Van Someren +5 more
TL;DR: Light has a modest benefit in improving some cognitive and noncognitive symptoms of dementia and is recommended only in combination with light to counteract the adverse effect of melatonin on mood.
Journal ArticleDOI
Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients.
TL;DR: The observations strongly support the hypothesis that CRH neurons in the PVN are hyperactivated in major depressed patients, and might be causally related to at least part of the symptomatology of depression.