W
Wolfgang Siegfried
Researcher at National Institutes of Health
Publications - 1
Citations - 975
Wolfgang Siegfried is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Messenger RNA & Genetic enhancement. The author has an hindex of 1, co-authored 1 publications receiving 963 citations.
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Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo
Melissa A. Rosenfeld,Wolfgang Siegfried,Kunihiko Yoshimura,Koichi Yoneyama,Masashi Fukayama,L Stier,Paavo K. Paakko,Pascale Gilardi,L D Stratford-Perricaudet,Michel Perricaudet,Sophie Jallat,Andrea Pavirani,Jean-Pierre Lecocq,Ronald G. Crystal +13 more
TL;DR: The respiratory epithelium is a potential site for somatic gene therapy for the common hereditary disorders alpha 1-antitrypsin (alpha 1AT) deficiency and cystic fibrosis by infecting epithelial cells of the cotton rat respiratory tract in vitro and in vivo.