Wolfgang Wagner

Bio: Wolfgang Wagner is an academic researcher from Vienna University of Technology. The author has contributed to research in topics: Large Hadron Collider & Top quark. The author has an hindex of 156, co-authored 2342 publications receiving 123391 citations. Previous affiliations of Wolfgang Wagner include University of Pennsylvania & University of Amsterdam.

Collective symbolic coping with new technology: knowledge, images and public discourse

Abstract: Using data from policy analyses, media analyses and a European-wide survey about public perceptions of biotechnology conducted in 1996 and again in 1999, it is shown how a country's public develops an everyday understanding of a new technology (genetic modification) construed as potentially harmful by the media. To understand the reliance on images and related beliefs, we propose a theory of collective symbolic coping. It identifies four steps: first, the creation of awareness; second, production of divergent images; third, convergence upon a couple of dominant images in the public sphere; fourth, normalization. It is suggested that symbolic coping occurs in countries where a recent increase in policy activity and of media reporting has alerted the public; that this public show a high proportion of beliefs in menacing images; that these beliefs are relatively independent of pre-existing popular science knowledge; and that they are functionally equivalent to scientific knowledge in providing judgmental confidence and reducing self-ascribed ignorance. These propositions are shown to be true in Austria and Greece. Several implications of the theory are discussed, including social representation theory and public understanding of science.

Molecular and Secretory Profiles of Human Mesenchymal Stromal Cells and Their Abilities to Maintain Primitive Hematopoietic Progenitors

Abstract: Mesenchymal stromal cells (MSC) provide a supportive cellular microenvironment and are able to maintain the self-renewal capacity of hematopoietic progenitor cells (HPC) Isolation procedures for MSC vary extensively and this may influence their biologic properties In this study, we have compared human MSC isolated from bone marrow (BM) using two culture conditions, from cord blood (CB) and from adipose tissue (AT) The ability to maintain long-term culture-initiating cell (LTC-IC) frequency and a primitive CD34 + CD38 immunophenotype was significantly higher for MSC derived from BM and CB compared to those from AT These results were in line with a significantly higher adhesion of HPC to MSC from BM and CB versus MSC from AT We have compared the cytokine production of MSC by cytokine antibody arrays, ELISA and by a cytometric bead array There were reproducible differences in the chemokine secretion profiles of various MSC preparations but there was no clear concordance with differences in their potential to maintain primitive function of HPC Global gene expression profiles of MSC preparations were analyzed and showed that adhesion proteins including cadherin-11, N-cadherin, VCAM1, NCAM1 and integrins were highly expressed in MSC preparations derived from BM and CB Thus MSC from BM and CB are superior to MSC from AT for maintenance of primitive HPC The latter property is associated with specific molecular profiles indicating the significance of cell-cell junctions but not with secretory profiles

Search for high-mass diboson resonances with boson-tagged jets in proton-proton collisions at √s=8 TeV with the ATLAS detector

Abstract: A search is performed for narrow resonances decaying into WW, WZ, or ZZ boson pairs using 20.3 fb(-1) of proton-proton collision data at a centre-of-mass energy of root s = TeV recorded with the AT ...

Search for dark matter in events with a hadronically decaying W or Z boson and missing transverse momentum in pp collisions at √s = 8 TeV with the ATLAS detector

Abstract: A search is presented for dark matter pair production in association with a W or Z boson in pp collisions representing 20.3 fb(-1) of integrated luminosity at root s = 8 TeV using data recorded with the ATLAS detector at the Large Hadron Collider. Events with a hadronic jet with the jet mass consistent with a W or Z boson, and with large missing transverse momentum are analyzed. The data are consistent with the standard model expectations. Limits are set on the mass scale in effective field theories that describe the interaction of dark matter and standard model particles, and on the cross section of Higgs production and decay to invisible particles. In addition, cross section limits on the anomalous production of W or Z bosons with large missing transverse momentum are set in two fiducial regions.

Measurements of Higgs boson production and couplings in the four-lepton channel in pp collisions at center-of-mass energies of 7 and 8 TeV with the ATLAS detector

Abstract: The final ATLAS Run 1 measurements of Higgs boson production and couplings in the decay channel H -> ZZ* -> l(+)l(-)l(+)l'(-), where l, l' = e or mu, are presented. These measurements were performed using pp collision data corresponding to integrated luminosities of 4.5 and 20.3 fb(-1) at center-of-mass energies of 7 and 8 TeV, respectively, recorded with the ATLAS detector at the LHC. The H -> ZZ* -> 4l signal is observed with a significance of 8.1 standard deviations, with an expectation of 6.2 standard deviations, at m(H) = 125.36 GeV, the combined ATLAS measurement of the Higgs boson mass from the H -> gamma gamma and H -> ZZ* -> 4l channels. The production rate relative to the Standard Model expectation, the signal strength, is measured in four different production categories in the H -> ZZ* -> 4l channel. The measured signal strength, at this mass, and with all categories combined, is 1.44(-0.33)(+0.40). The signal strength for Higgs boson production in gluon fusion or in association with (tt) over bar or (bb) over bar pairs is found to be 1.7(-0.4)(+0.5), while the signal strength for vector-boson fusion combined with WH/ZH associated production is found to be 0.3(-0.9)(+1.6).

I and i

Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

Fast parallel algorithms for short-range molecular dynamics

Abstract: Three parallel algorithms for classical molecular dynamics are presented. The first assigns each processor a fixed subset of atoms; the second assigns each a fixed subset of inter-atomic forces to compute; the third assigns each a fixed spatial region. The algorithms are suitable for molecular dynamics models which can be difficult to parallelize efficiently—those with short-range forces where the neighbors of each atom change rapidly. They can be implemented on any distributed-memory parallel machine which allows for message-passing of data between independently executing processors. The algorithms are tested on a standard Lennard-Jones benchmark problem for system sizes ranging from 500 to 100,000,000 atoms on several parallel supercomputers--the nCUBE 2, Intel iPSC/860 and Paragon, and Cray T3D. Comparing the results to the fastest reported vectorized Cray Y-MP and C90 algorithm shows that the current generation of parallel machines is competitive with conventional vector supercomputers even for small problems. For large problems, the spatial algorithm achieves parallel efficiencies of 90% and a 1840-node Intel Paragon performs up to 165 faster than a single Cray C9O processor. Trade-offs between the three algorithms and guidelines for adapting them to more complex molecular dynamics simulations are also discussed.

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。