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Xiaojun Julia Liang
Researcher at University of Tübingen
Publications - 1
Citations - 14
Xiaojun Julia Liang is an academic researcher from University of Tübingen. The author has contributed to research in topics: Janus kinase & Janus kinase 3. The author has an hindex of 1, co-authored 1 publications receiving 2 citations.
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Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK.
Michael Forster,Xiaojun Julia Liang,Martin Schröder,Martin Schröder,Stefan Gerstenecker,Apirat Chaikuad,Apirat Chaikuad,Stefan Knapp,Stefan Knapp,Stefan Laufer,Matthias Gehringer +10 more
TL;DR: A novel class of dual BMX/BTK inhibitors were designed from irreversible inhibitors of Janus kinase (JAK) 3 targeting a cysteine located within the solvent-exposed front region of the ATP binding pocket, enabling the achievement of high selectivity over JAK3 and certain other kinases harboring a sterically demanding residue at this position.