Xiaotong Cheng

TL;DR: In vitro and in vivo results indicate that this strategy of tumor starvation and phototherapy significantly enhances mild‐temperature tumor PTT efficiency, which could inspire people to design more delicate platforms combining mild-temperature PTT with other therapeutic methods for more efficient cancer treatment.

TL;DR: A review of GSH depletion-based cancer therapies can be found in this article, where the authors present some current challenges and future perspectives for GSH-depleting nanomedicine based cancer therapies.

TL;DR: The work highlights the feasibility of using cationic and ultrasmall metal-free CDs to eliminate and inhibit Gram-positive bacterial biofilms, which represents a highly effective strategy to cope with refractory biofilm-associated infections.

TL;DR: The facilely prepared histidine-capped gold nanoclusters (Au NCs@His) were adopted as a radiosensitizer with a high sensitization enhancement ratio and can decrease the intracellular GSH level, thus preventing the generated reactive oxygen species (ROS) from being consumed by GSH.

TL;DR: Theranostic nanoparticles capable of mitochondrial targeting/imaging, cancer/normal cell differentiation, early stage cancer diagnosis, and mitochondria-based photothermal therapy (PTT) were developed and achieved excellent photothermal tumor ablation both in vitro and in vivo.